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Journal of the American Chemical Society|May 3, 2008
Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: bryostatin look-alikes that mimic phorbol ester functionGary E Keck, Matthew B Kraft, Anh P Truong, et al.Journal of Medicinal Chemistry|November 14, 2024
Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell DiseaseJohn Ryan Kerrigan, Noel M Thomsen, Artiom Cernijenko, et al.Journal of Medicinal Chemistry|November 9, 2018
Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA)Atwood K Cheung, Brian Hurley, Ryan Kerrigan, et al.Science (New York, N.Y.)|July 4, 2024
A molecular glue degrader of the WIZ transcription factor for fetal hemoglobin inductionPamela Y Ting, Sneha Borikar, John Ryan Kerrigan, et al.Journal of Medicinal Chemistry|May 19, 2026
Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical ValidationDean P Phillips, Phil B Alper, Charles Y Cho, et al.Pageof 1