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Bioorganic & Medicinal Chemistry Letters|December 28, 2010
Azaindoles as potent CRTH2 receptor antagonistsDaniel Simard, Yves Leblanc, Carl Berthelette, et al.Bioorganic & Medicinal Chemistry Letters|May 18, 2010
Discovery of 4-[1-[([1-[4-(trifluoromethyl)benzyl]-1H-indol-7-yl]carbonyl)amino]cyclopropyl]benzoic acid (MF-766), a highly potent and selective EP4 antagonist for treating inflammatory painJohn Colucci, Michael Boyd, Carl Berthelette, et al.Bioorganic & Medicinal Chemistry Letters|November 11, 2006
In vitro biotransformations of the prostaglandin D2 (DP) antagonist MK-0524 and synthesis of metabolitesDeborah A Nicoll-Griffith, Carmai Seto, Yves Aubin, et al.Bioorganic & Medicinal Chemistry Letters|April 10, 2007
Metabolic activation of indole-containing prostaglandin D2 receptor 1 antagonists: impacts of glutathione trapping and glucuronide conjugation on covalent bindingJean-François Lévesque, Stephen H Day, Nathalie Chauret, et al.Bioorganic & Medicinal Chemistry Letters|March 15, 2006
Identification of an indole series of prostaglandin D2 receptor antagonistsClaudio F Sturino, Nicolas Lachance, Michael Boyd, et al.Bioorganic & Medicinal Chemistry Letters|November 26, 2010
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseasesMichel Gallant, Christian Beaulieu, Carl Berthelette, et al.Journal of Medicinal Chemistry|February 16, 2007
Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524)Claudio F Sturino, Gary O'Neill, Nicolas Lachance, et al.Pageof 2