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Proceedings of the National Academy of Sciences of the United States of America|June 27, 2013
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain sheddingThorsten Maretzky, David R McIlwain, Priya Darshinee A Issuree, et al.Nature Neuroscience|June 14, 2011
TACE (ADAM17) inhibits Schwann cell myelinationRosa La Marca, Federica Cerri, Keisuke Horiuchi, et al.FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|February 28, 2020
Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domainsBeiyu Tang, Xue Li, Thorsten Maretzky, et al.Journal of Cell Science|October 29, 2010
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic siteSylvain M Le Gall, Thorsten Maretzky, Priya D A Issuree, et al.Circulation Research|January 30, 2010
Pathological neovascularization is reduced by inactivation of ADAM17 in endothelial cells but not in pericytesGisela Weskamp, Karen Mendelson, Steve Swendeman, et al.Cancer Research|June 3, 2009
Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancerThorsten Maretzky, Sylvain M Le Gall, Susanne Worpenberg-Pietruk, et al.Angiogenesis|February 5, 2018
Glomerular endothelial cell maturation depends on ADAM10, a key regulator of Notch signalingGregory Farber, Romulo Hurtado, Sarah Loh, et al.Molecular Biology of the Cell|January 23, 2009
ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alphaSylvain M Le Gall, Pierre Bobé, Karina Reiss, et al.The Journal of Experimental Medicine|May 9, 2012
Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiationClaus-Werner Franzke, Cristina Cobzaru, Antigoni Triantafyllopoulou, et al.The Journal of Biological Chemistry|April 26, 2003
Impaired trafficking and activation of tumor necrosis factor-alpha-converting enzyme in cell mutants defective in protein ectodomain sheddingAldo Borroto, Soraya Ruiz-Paz, Teresa Villanueva de la Torre, et al.Pageof 10