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Nature Communications|August 2, 2022
Segregated cation flux by TPC2 biases Ca<sup>2+</sup> signaling through lysosomesYu Yuan, Dawid Jaślan, Taufiq Rahman, et al.Frontiers in Immunology|November 10, 2025
Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCCLina Ouologuem, Anna Kübler, Sarah Ouologuem, et al.Journal of Medicinal Chemistry|March 15, 2023
Inclusion of Nitrofurantoin into the Realm of Cancer Chemotherapy via Biology-Oriented Synthesis and Drug RepurposingPerihan A Elzahhar, Hisham A Nematalla, Houssam Al-Koussa, et al.Nature Communications|November 20, 2024
Rab7a is an enhancer of TPC2 activity regulating melanoma progression through modulation of the GSK3β/β-Catenin/MITF-axisCarla Abrahamian, Rachel Tang, Rebecca Deutsch, et al.EMBO Molecular Medicine|August 5, 2022
TPC2 rescues lysosomal storage in mucolipidosis type IV, Niemann-Pick type C1, and Batten diseaseAnna Scotto Rosato, Einar K Krogsaeter, Dawid Jaślan, et al.Pageof 2