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Briefings in Bioinformatics|February 21, 2022
Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structuresQisheng Pan, Thanh Binh Nguyen, David B Ascher, et al.
Journal of Pharmaceutical Sciences|December 25, 2014
Practical lessons in murine thoracic lymph duct cannulations: observations in female and male mice across four different strains that impact on "cannulatability"Suzanne M Caliph, David M Shackleford, David B Ascher, et al.
Methods in Enzymology|July 3, 2017
DNA-PKcs, Allostery, and DNA Double-Strand Break Repair: Defining the Structure and Setting the StageDimitri Y Chirgadze, David B Ascher, Tom L Blundell, et al.
Methods in Molecular Biology (Clifton, N.J.)|November 8, 2022
Using Graph-Based Signatures to Guide Rational Antibody EngineeringDavid B Ascher, Lisa M Kaminskas, Yoochan Myung, et al.
Computational and Structural Biotechnology Journal|October 22, 2024
Insights into the structure of NLR family member X1: Paving the way for innovative drug discoveryShannon Jewell, Thanh Binh Nguyen, David B Ascher, et al.
Biochemical Society Transactions|April 15, 2017
Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistanceArun Prasad Pandurangan, David B Ascher, Sherine E Thomas, et al.
Nucleic Acids Research|May 20, 2017
SDM: a server for predicting effects of mutations on protein stabilityArun Prasad Pandurangan, Bernardo Ochoa-Montaño, David B Ascher, et al.
Scientific Reports|January 23, 2016
In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activityDouglas E V Pires, Jing Chen, Tom L Blundell, et al.
Science (New York, N.Y.)|February 4, 2017
DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repairBancinyane L Sibanda, Dimitri Y Chirgadze, David B Ascher, et al.
Acta Crystallographica. Section F, Structural Biology Communications|March 7, 2014
Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-βGabriela A N Crespi, David B Ascher, Michael W Parker, et al.
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