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Biochemical Society Transactions|November 24, 2022
Activities and binding partners of E3 ubiquitin ligase DTX3L and its roles in cancerCarlos Vela-Rodríguez, Lari Lehtiö
SLAS Discovery : Advancing Life Sciences R & D|August 14, 2023
Discovery of DTX3L inhibitors through a homogeneous FRET-based assay that monitors formation and removal of poly-ubiquitin chainsCarlos Vela-Rodríguez, Ilaria Scarpulla, Yashwanth Ashok, et al.
Trends in Biochemical Sciences|March 19, 2026
Parallels and crosstalk of ADP-ribosylation and ubiquitinationCarlos Vela-Rodríguez, Albert Galera-Prat, Jonathan N Pruneda, et al.
The Biochemical Journal|January 17, 2022
Reconstitution of the DTX3L-PARP9 complex reveals determinants for high-affinity heterodimerization and multimeric assemblyYashwanth Ashok, Carlos Vela-Rodríguez, Chunsong Yang, et al.
Scientific Reports|May 17, 2026
Targeting collagen biosynthesis by small molecules inhibiting the function of the peptide-substrate-binding domain of collagen prolyl 4-hydroxylasesBukunmi Adediran, Carlos Vela-Rodríguez, Sudarshan Murthy, et al.
ACS Chemical Biology|November 8, 2023
Synthetic Dual Cysteine-ADP Ribosylated Peptides from the Androgen Receptor are Recognized by the DTX3L/PARP9 ComplexSven Wijngaarden, Chunsong Yang, Carlos Vela-Rodríguez, et al.
Scientific Reports|July 25, 2020
A FRET-based high-throughput screening platform for the discovery of chemical probes targeting the scaffolding functions of human tankyrasesSven T Sowa, Carlos Vela-Rodríguez, Albert Galera-Prat, et al.
Journal of Structural Biology|January 6, 2026
Biophysical characterization of zinc and DNA binding properties of MRN complex interacting proteinSamina Kazi, Ezeogo Obaji, Johan Pääkkönen, et al.
Iscience|July 24, 2025
The E3 ubiquitin ligase DTX3L and the deubiquitinase USP28 fine-tune DNA repair through mutual regulation of their protein levelsDaniela Mennerich, Yashwanth Ashok, Carlos Vela-Rodríguez, et al.
Protein Science : a Publication of the Protein Society|March 21, 2024
Oligomerization mediated by the D2 domain of DTX3L is critical for DTX3L-PARP9 reading function of mono-ADP-ribosylated androgen receptorCarlos Vela-Rodríguez, Chunsong Yang, Heli I Alanen, et al.
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