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Cancer Research|January 31, 2016
EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF ReceptorYong Jia, Jose Juarez, Jie Li, et al.Nature Communications|March 12, 2015
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancerMatthew J Niederst, Lecia V Sequist, John T Poirier, et al.Nature Medicine|February 2, 2016
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibitionAaron N Hata, Matthew J Niederst, Hannah L Archibald, et al.Science Translational Medicine|June 28, 2023
Targeting CCR7-PI3Kγ overcomes resistance to tyrosine kinase inhibitors in ALK-rearranged lymphomaCristina Mastini, Marco Campisi, Enrico Patrucco, et al.Biorxiv : the Preprint Server for Biology|April 17, 2026
Transcription Factor Subtype Governs Response and Resistance to DLL3-Directed T-Cell Engagement in Small Cell Lung CancerDamien Vasseur, Shin Saito, Gunsagar S Gulati, et al.Science Translational Medicine|May 26, 2017
The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activationDavid P Kodack, Vasileios Askoxylakis, Gino B Ferraro, et al.The Journal of Clinical Investigation|September 24, 2025
USP10/GSK3β-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancerNishi Kumari, Sarah Ce Wright, Christopher M Witham, et al.Proceedings of the National Academy of Sciences of the United States of America|March 5, 2015
Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancerAnthony C Faber, Anna F Farago, Carlotta Costa, et al.Cancer Cell|February 10, 2016
Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy CombinationJungoh Ham, Carlotta Costa, Renata Sano, et al.Scientific Reports|January 15, 2021
SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanismsYe Wang, Morvarid Mohseni, Angelo Grauel, et al.Pageof 4