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Bioorganic & Medicinal Chemistry Letters|February 16, 2008
PB183, a sigma receptor ligand, as a potential PET probe for the imaging of prostate adenocarcinomaNicola Antonio Colabufo, Carmen Abate, Marialessandra Contino, et al.Pharmaceuticals (Basel, Switzerland)|December 31, 2025
Pridopidine, a Potent and Selective Therapeutic Sigma-1 Receptor (S1R) Agonist for Treating Neurodegenerative DiseasesNoga Gershoni Emek, Andrew M Tan, Michal Geva, et al.Current Medicinal Chemistry|April 4, 2023
Structure-Activity Relationships and Therapeutic Potential of Purinergic P2X7 Receptor AntagonistsImane Ghafir El Idrissi, Sabina Podlewska, Carmen Abate, et al.Journal of Medicinal Chemistry|April 16, 2004
4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activityFrancesco Berardi, Savina Ferorelli, Carmen Abate, et al.Journal of Medicinal Chemistry|October 22, 2009
Exploring the importance of piperazine N-atoms for sigma(2) receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28)Francesco Berardi, Carmen Abate, Savina Ferorelli, et al.Chemmedchem|November 12, 2010
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Δ(8)-Δ(7) sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activityCarmen Abate, Mauro Niso, Marialessandra Contino, et al.Journal of Medicinal Chemistry|July 13, 2011
Fluorescent derivatives of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a tool for uptake and cellular localization studies in pancreatic tumor cellsCarmen Abate, John R Hornick, Dirk Spitzer, et al.BMC Cancer|January 15, 2017
Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancerMaria Laura Pati, John R Hornick, Mauro Niso, et al.Chemmedchem|August 15, 2012
2-Aminopyridine derivatives as potential σ(2) receptor antagonistsCarmen Abate, Savina Ferorelli, Mauro Niso, et al.European Journal of Medicinal Chemistry|December 3, 2014
From mixed sigma-2 receptor/P-glycoprotein targeting agents to selective P-glycoprotein modulators: small structural changes address the mechanism of interaction at the efflux pumpCarmen Abate, Maria Laura Pati, Marialessandra Contino, et al.Pageof 9