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Bioorganic & Medicinal Chemistry Letters|August 27, 2023
Identification of covalent fragment inhibitors for Plasmodium falciparum UCHL3 with anti-malarial efficacyRyan D Imhoff, Melissa R Rosenthal, Kutub Ashraf, et al.Journal of Molecular Medicine (Berlin, Germany)|August 19, 2020
Immuno-epidemiology and pathophysiology of coronavirus disease 2019 (COVID-19)Omalla A Olwenyi, Shetty Ravi Dyavar, Arpan Acharya, et al.Plos Pathogens|June 7, 2019
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agentsBarbara H Stokes, Euna Yoo, James M Murithi, et al.Journal of the American Chemical Society|August 16, 2018
Defining the Determinants of Specificity of Plasmodium Proteasome InhibitorsEuna Yoo, Barbara H Stokes, Hanna de Jong, et al.ACS Infectious Diseases|October 31, 2018
Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265John White, Satish K Dhingra, Xiaoyi Deng, et al.Cell|August 16, 2014
Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunateAndreas Martin Lisewski, Joel P Quiros, Caroline L Ng, et al.Molecular Microbiology|April 14, 2016
CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugsCaroline L Ng, Giulia Siciliano, Marcus C S Lee, et al.The Lancet. Infectious Diseases|April 2, 2017
Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised studyJames S McCarthy, Julie Lotharius, Thomas Rückle, et al.Nature Communications|March 7, 2017
A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologueEbere Sonoiki, Caroline L Ng, Marcus C S Lee, et al.The Journal of Biological Chemistry|June 12, 2013
UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cellsRalf Brunner, Caroline L Ng, Hamed Aissaoui, et al.Pageof 3