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The Lancet. Infectious Diseases|June 18, 2018
Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a studyAlejandro Llanos-Cuentas, Martin Casapia, Raúl Chuquiyauri, et al.Nature Microbiology|August 16, 2017
Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activityManu Vanaerschot, Leonardo Lucantoni, Tao Li, et al.Cell Chemical Biology|March 24, 2023
Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasomeIoanna Deni, Barbara H Stokes, Kurt E Ward, et al.Plos Medicine|October 5, 2016
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy ModelingAmélie Le Bihan, Ruben de Kanter, Iñigo Angulo-Barturen, et al.Science Translational Medicine|July 17, 2015
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malariaMargaret A Phillips, Julie Lotharius, Kennan Marsh, et al.Pageof 3