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Journal of Medicinal Chemistry
|
June 23, 2009
Discovery of molecular switches that modulate modes of metabotropic glutamate receptor subtype 5 (mGlu5) pharmacology in vitro and in vivo within a series of functionalized, regioisomeric 2- and 5-(phenylethynyl)pyrimidines
Sameer Sharma, Jeffrey Kedrowski, Jerri M Rook, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 10, 2016
Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypes
Alexander R Geanes, Hykeyung P Cho, Kellie D Nance, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
July 14, 2006
Antiallodynic and antihyperalgesic effects of selective competitive GLUK5 (GluR5) ionotropic glutamate receptor antagonists in the capsaicin and carrageenan models in rats
Carrie K Jones, Andrew Alt, Ann Marie Ogden, et al.
Neuropharmacology
|
May 2, 2012
The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease
Kari A Johnson, Carrie K Jones, Mohammed N Tantawy, et al.
Synapse (New York, N.Y.)
|
May 18, 2011
Impact of isoflurane anesthesia on D2 receptor occupancy by [18F]fallypride measured by microPET with a modified Logan plot
Mohammed N Tantawy, Todd E Peterson, Carrie K Jones, et al.
ACS Medicinal Chemistry Letters
|
September 16, 2014
Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D4 Receptor with in Vivo Activity
Cynthia B Berry, Michael Bubser, Carrie K Jones, et al.
Neuropharmacology
|
March 10, 2015
Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and L-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator and an orthosteric agonist
Hanna Iderberg, Natallia Maslava, Analisa D Thompson, et al.
Frontiers in Neuroscience
|
July 19, 2021
Partial mGlu<sub>5</sub> Negative Allosteric Modulator M-5MPEP Demonstrates Antidepressant-Like Effects on Sleep Without Affecting Cognition or Quantitative EEG
Kimberly M Holter, Alex D Lekander, Christina M LaValley, et al.
ACS Pharmacology & Translational Science
|
April 8, 2020
<i>In Vitro</i> to <i>in Vivo</i> Translation of Allosteric Modulator Concentration-Effect Relationships: Implications for Drug Discovery
Karen J Gregory, Thomas M Bridges, Rocco G Gogliotti, et al.
The Journal of Biological Chemistry
|
July 29, 2014
Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibition
Thomas H Oguin, Shalini Sharma, Amanda D Stuart, et al.
Page
of 16
Search research articles
Search
Showing results (31-40 of 157) with videos related to
Sort By:
Page
of 16
Journal of Medicinal Chemistry
|
June 23, 2009
Discovery of molecular switches that modulate modes of metabotropic glutamate receptor subtype 5 (mGlu5) pharmacology in vitro and in vivo within a series of functionalized, regioisomeric 2- and 5-(phenylethynyl)pyrimidines
Sameer Sharma, Jeffrey Kedrowski, Jerri M Rook, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 10, 2016
Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypes
Alexander R Geanes, Hykeyung P Cho, Kellie D Nance, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
July 14, 2006
Antiallodynic and antihyperalgesic effects of selective competitive GLUK5 (GluR5) ionotropic glutamate receptor antagonists in the capsaicin and carrageenan models in rats
Carrie K Jones, Andrew Alt, Ann Marie Ogden, et al.
Neuropharmacology
|
May 2, 2012
The metabotropic glutamate receptor 8 agonist (S)-3,4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease
Kari A Johnson, Carrie K Jones, Mohammed N Tantawy, et al.
Synapse (New York, N.Y.)
|
May 18, 2011
Impact of isoflurane anesthesia on D2 receptor occupancy by [18F]fallypride measured by microPET with a modified Logan plot
Mohammed N Tantawy, Todd E Peterson, Carrie K Jones, et al.
ACS Medicinal Chemistry Letters
|
September 16, 2014
Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D4 Receptor with in Vivo Activity
Cynthia B Berry, Michael Bubser, Carrie K Jones, et al.
Neuropharmacology
|
March 10, 2015
Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and L-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator and an orthosteric agonist
Hanna Iderberg, Natallia Maslava, Analisa D Thompson, et al.
Frontiers in Neuroscience
|
July 19, 2021
Partial mGlu<sub>5</sub> Negative Allosteric Modulator M-5MPEP Demonstrates Antidepressant-Like Effects on Sleep Without Affecting Cognition or Quantitative EEG
Kimberly M Holter, Alex D Lekander, Christina M LaValley, et al.
ACS Pharmacology & Translational Science
|
April 8, 2020
<i>In Vitro</i> to <i>in Vivo</i> Translation of Allosteric Modulator Concentration-Effect Relationships: Implications for Drug Discovery
Karen J Gregory, Thomas M Bridges, Rocco G Gogliotti, et al.
The Journal of Biological Chemistry
|
July 29, 2014
Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibition
Thomas H Oguin, Shalini Sharma, Amanda D Stuart, et al.
Page
of 16