Search research articles
Contact Us
Filters
Showing results (71-80 of 157) with videos related to
Page
of 16
Sort By:
Human Molecular Genetics
|
March 4, 2016
mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome
Rocco G Gogliotti, Rebecca K Senter, Jerri M Rook, et al.
Neuropharmacology
|
July 22, 2017
Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M<sub>4</sub> PAM VU0467154
Robert W Gould, Michael D Grannan, Barak W Gunter, et al.
ACS Chemical Biology
|
August 20, 2014
Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenics
Hyekyung P Cho, Pedro M Garcia-Barrantes, John T Brogan, et al.
Biological Psychiatry
|
April 26, 2020
Acetylcholine Muscarinic M<sub>4</sub> Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents
Leigh C Walker, Alice E Berizzi, Nicola A Chen, et al.
Journal of Medicinal Chemistry
|
November 26, 2014
Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM)
Lindsey C Morris, Kellie D Nance, Patrick R Gentry, et al.
Neuron
|
September 13, 2016
Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release
Daniel J Foster, Jermaine M Wilson, Daniel H Remke, et al.
ACS Chemical Neuroscience
|
July 22, 2016
Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers
Colleen M Niswender, Carrie K Jones, Xin Lin, et al.
Journal of Medicinal Chemistry
|
September 25, 2018
Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu<sub>4</sub>)
Sean R Bollinger, Darren W Engers, Joseph D Panarese, et al.
Molecular Pharmacology
|
May 2, 2009
A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning
Douglas J Sheffler, Richard Williams, Thomas M Bridges, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 4, 2013
Biotransformation of a novel positive allosteric modulator of metabotropic glutamate receptor subtype 5 contributes to seizure-like adverse events in rats involving a receptor agonism-dependent mechanism
Thomas M Bridges, Jerri M Rook, Meredith J Noetzel, et al.
Page
of 16
Search research articles
Search
Showing results (71-80 of 157) with videos related to
Sort By:
Page
of 16
Human Molecular Genetics
|
March 4, 2016
mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome
Rocco G Gogliotti, Rebecca K Senter, Jerri M Rook, et al.
Neuropharmacology
|
July 22, 2017
Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M<sub>4</sub> PAM VU0467154
Robert W Gould, Michael D Grannan, Barak W Gunter, et al.
ACS Chemical Biology
|
August 20, 2014
Chemical modulation of mutant mGlu1 receptors derived from deleterious GRM1 mutations found in schizophrenics
Hyekyung P Cho, Pedro M Garcia-Barrantes, John T Brogan, et al.
Biological Psychiatry
|
April 26, 2020
Acetylcholine Muscarinic M<sub>4</sub> Receptors as a Therapeutic Target for Alcohol Use Disorder: Converging Evidence From Humans and Rodents
Leigh C Walker, Alice E Berizzi, Nicola A Chen, et al.
Journal of Medicinal Chemistry
|
November 26, 2014
Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM)
Lindsey C Morris, Kellie D Nance, Patrick R Gentry, et al.
Neuron
|
September 13, 2016
Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release
Daniel J Foster, Jermaine M Wilson, Daniel H Remke, et al.
ACS Chemical Neuroscience
|
July 22, 2016
Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers
Colleen M Niswender, Carrie K Jones, Xin Lin, et al.
Journal of Medicinal Chemistry
|
September 25, 2018
Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu<sub>4</sub>)
Sean R Bollinger, Darren W Engers, Joseph D Panarese, et al.
Molecular Pharmacology
|
May 2, 2009
A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning
Douglas J Sheffler, Richard Williams, Thomas M Bridges, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals
|
July 4, 2013
Biotransformation of a novel positive allosteric modulator of metabotropic glutamate receptor subtype 5 contributes to seizure-like adverse events in rats involving a receptor agonism-dependent mechanism
Thomas M Bridges, Jerri M Rook, Meredith J Noetzel, et al.
Page
of 16