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Frontiers in Genetics|September 14, 2012
Rapamycin has a biphasic effect on insulin sensitivity in C2C12 myotubes due to sequential disruption of mTORC1 and mTORC2Lan Ye, Behzad Varamini, Dudley W Lamming, et al.
Nature Communications|March 22, 2024
An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathwayGrace Y Liu, Patrick Jouandin, Raymond E Bahng, et al.
Biorxiv : the Preprint Server for Biology|June 9, 2023
An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathwayGrace Y Liu, Patrick Jouandin, Raymond E Bahng, et al.
Science (New York, N.Y.)|November 5, 2011
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPaseRoberto Zoncu, Liron Bar-Peled, Alejo Efeyan, et al.
Nature|August 4, 2016
Mechanism of arginine sensing by CASTOR1 upstream of mTORC1Robert A Saxton, Lynne Chantranupong, Kevin E Knockenhauer, et al.
Science (New York, N.Y.)|September 5, 2015
Identification of an oncogenic RAB proteinDouglas B Wheeler, Roberto Zoncu, David E Root, et al.
Nature Methods|August 25, 2006
Genome-scale loss-of-function screening with a lentiviral RNAi libraryDavid E Root, Nir Hacohen, William C Hahn, et al.
Cancer Research|February 26, 2013
Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATRQingsong Liu, Chunxiao Xu, Sivapriya Kirubakaran, et al.
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