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Current Protocols|January 18, 2022
Measuring mRNA Decay with Roadblock-qPCRMaegan J Watson, Carson C Thoreen
Cell|May 19, 2009
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survivalTimothy R Peterson, Mathieu Laplante, Carson C Thoreen, et al.
Molecular Cell|March 28, 2007
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinaseYasemin Sancak, Carson C Thoreen, Timothy R Peterson, et al.
Developmental Cell|December 5, 2006
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1David A Guertin, Deanna M Stevens, Carson C Thoreen, et al.
Biorxiv : the Preprint Server for Biology|November 24, 2025
Larp1 supports brain growth and spatial memory via post-transcriptional control of the translation machineryMark S Williams, Maegan J Watson, Carson C Thoreen
The Journal of Biological Chemistry|January 20, 2009
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1Carson C Thoreen, Seong A Kang, Jae Won Chang, et al.
Bioorganic & Medicinal Chemistry Letters|May 31, 2011
Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stabilityQingsong Liu, Jinhua Wang, Seong A Kang, et al.
Cell Reports|May 13, 2017
mTORC1 Balances Cellular Amino Acid Supply with Demand for Protein Synthesis through Post-transcriptional Control of ATF4Yeonwoo Park, Andrea Reyna-Neyra, Lucas Philippe, et al.
Methods in Molecular Biology (Clifton, N.J.)|November 30, 2011
Development of ATP-competitive mTOR inhibitorsQingsong Liu, Seong A Kang, Carson C Thoreen, et al.
Nucleic Acids Research|December 16, 2017
La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory regionLucas Philippe, Jean-Jacques Vasseur, Françoise Debart, et al.
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