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Drug Discovery Today|March 19, 2022
Translating pharmacology models effectively to predict therapeutic benefitSherri Dudal, Caterina Bissantz, Antonello Caruso, et al.ACS Medicinal Chemistry Letters|June 20, 2020
Discovery of RO7185876, a Highly Potent γ-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer's DiseaseHasane Ratni, Andre Alker, Bjoern Bartels, et al.Journal of Medicinal Chemistry|January 18, 2020
Discovery of Balovaptan, a Vasopressin 1a Receptor Antagonist for the Treatment of Autism Spectrum DisorderPatrick Schnider, Caterina Bissantz, Andreas Bruns, et al.Journal of Medicinal Chemistry|February 16, 2016
A Real-World Perspective on Molecular DesignBernd Kuhn, Wolfgang Guba, Jérôme Hert, et al.Bioorganic & Medicinal Chemistry Letters|July 9, 2013
Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonistsHenrietta Dehmlow, Rubén Alvarez Sánchez, Stephan Bachmann, et al.Frontiers in Pharmacology|July 29, 2024
RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal modelsUwe Grether, Richard H Foxton, Sabine Gruener, et al.Nature|January 3, 2024
A novel antibiotic class targeting the lipopolysaccharide transporterClaudia Zampaloni, Patrizio Mattei, Konrad Bleicher, et al.Pageof 4