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Oncotarget|February 1, 2014
Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sitesCatherine A Vaughan, Swati P Deb, Sumitra Deb, et al.JCI Insight|September 19, 2019
DNA replication in progenitor cells and epithelial regeneration after lung injury requires the oncoprotein MDM2Shilpa Singh, Catherine A Vaughan, Christopher Rabender, et al.Molecular Oncology|April 20, 2017
Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cellsCatherine A Vaughan, Shilpa Singh, Steven R Grossman, et al.The Journal of Clinical Investigation|April 11, 2017
Mutant p53 establishes targetable tumor dependency by promoting unscheduled replicationShilpa Singh, Catherine A Vaughan, Rebecca A Frum, et al.Biochemical and Biophysical Research Communications|September 20, 2012
Allele specific gain-of-function activity of p53 mutants in lung cancer cellsCatherine A Vaughan, Rebecca Frum, Isabella Pearsall, et al.Oncotarget|January 29, 2016
Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoterCatherine A Vaughan, Isabella Pearsall, Shilpa Singh, et al.Genes & Cancer|December 25, 2012
Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase AxlCatherine A Vaughan, Shilpa Singh, Brad Windle, et al.Archives of Biochemistry and Biophysics|December 27, 2011
p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activityCatherine A Vaughan, Shilpa Singh, Brad Windle, et al.Carcinogenesis|November 25, 2011
Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migrationW Andrew Yeudall, Catherine A Vaughan, Hiroshi Miyazaki, et al.Nature Communications|January 30, 2021
The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3Catherine A Vaughan, Shilpa Singh, Mark A Subler, et al.Pageof 1