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Proceedings of the National Academy of Sciences of the United States of America|February 17, 2021
Modulation of α1β3γ2 GABAA receptors expressed in X. laevis oocytes using a propofol photoswitch tethered to the transmembrane helixCecilia M Borghese, Hua-Yu L Wang, Stanton F McHardy, et al.
Neuropharmacology|August 1, 2020
Apremilast regulates acute effects of ethanol and other GABAergic drugs via protein kinase A-dependent signalingYuri A Blednov, Cecilia M Borghese, Michael P Dugan, et al.
Molecular Pharmacology|August 17, 2013
Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channelsStephanie A Heusser, Rebecca J Howard, Cecilia M Borghese, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 8, 2005
The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanolCecilia M Borghese, Signe í Stórustovu, Bjarke Ebert, et al.
Neuropharmacology|June 18, 2017
Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordinationYuri A Blednov, Cecilia M Borghese, Carlos I Ruiz, et al.
Science (New York, N.Y.)|September 23, 2017
Interacting amino acid replacements allow poison frogs to evolve epibatidine resistanceRebecca D Tarvin, Cecilia M Borghese, Wiebke Sachs, et al.
Nature Communications|July 2, 2025
A single main-chain hydrogen bond required to keep GABAA receptors closedCecilia M Borghese, Jason D Galpin, Samuel Eriksson Lidbrink, et al.
Anesthesiology|August 14, 2012
Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin miceCecilia M Borghese, Wei Xiong, S Irene Oh, et al.
Biochemical Pharmacology|March 19, 2022
(+)-Catharanthine potentiates the GABAA receptor by binding to a transmembrane site at the β(+)/α(-) interface near the TM2-TM3 loopHugo R Arias, Cecilia M Borghese, Allison L Germann, et al.
The Journal of Pharmacology and Experimental Therapeutics|November 1, 2011
Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcoholsCecilia M Borghese, Yuri A Blednov, Yu Quan, et al.
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