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European Journal of Nuclear Medicine and Molecular Imaging|August 27, 2024
Preclinical evaluation of the novel [18F]CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's diseaseFranziska Zajicek, Jeroen Verhaeghe, Stef De Lombaerde, et al.European Journal of Nuclear Medicine and Molecular Imaging|October 15, 2021
Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's diseaseDaniele Bertoglio, Jeroen Verhaeghe, Alan Miranda, et al.Molecular Neurobiology|January 9, 2020
Elevated Type 1 Metabotropic Glutamate Receptor Availability in a Mouse Model of Huntington's Disease: a Longitudinal PET StudyDaniele Bertoglio, Jeroen Verhaeghe, Špela Korat, et al.Journal of Molecular Medicine (Berlin, Germany)|December 18, 2025
Preclinical evaluation of [11C]CHDI-009R for quantification of mutant huntingtin aggregatesFranziska Zajicek, Liesbeth Everix, Annemie Van Eetveldt, et al.Plos One|March 20, 2018
Quantifying autophagy using novel LC3B and p62 TR-FRET assaysAlberto Bresciani, Maria Carolina Spiezia, Roberto Boggio, et al.Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|November 19, 2016
Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral CortexJenny Häggkvist, Miklós Tóth, Lenke Tari, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 4, 2012
Metabolism and pharmacokinetics of JM6 in mice: JM6 is not a prodrug for Ro-61-8048Maria G Beconi, Dawn Yates, Kathryn Lyons, et al.Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|July 17, 2019
Validation and noninvasive kinetic modeling of [11C]UCB-J PET imaging in miceDaniele Bertoglio, Jeroen Verhaeghe, Alan Miranda, et al.European Journal of Nuclear Medicine and Molecular Imaging|August 24, 2022
Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [11C]CHDI-00485180-R and [11C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtinAline Delva, Michel Koole, Kim Serdons, et al.International Journal of Molecular Sciences|July 27, 2022
Modelling the Human Blood-Brain Barrier in Huntington DiseaseDomenico Vignone, Odalys Gonzalez Paz, Ivan Fini, et al.Pageof 9