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ACS Medicinal Chemistry Letters|May 22, 2020
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 InteractionJesus M Ontoria, Ilaria Biancofiore, Paola Fezzardi, et al.Plos One|September 14, 2012
Oral administration of the pimelic diphenylamide HDAC inhibitor HDACi 4b is unsuitable for chronic inhibition of HDAC activity in the CNS in vivoMaria Beconi, Omar Aziz, Kim Matthews, et al.Journal of Medicinal Chemistry|February 11, 2012
Structure-based design of novel class II c-Met inhibitors: 2. SAR and kinase selectivity profiles of the pyrazolone seriesLongbin Liu, Mark H Norman, Matthew Lee, et al.Journal of Medicinal Chemistry|June 9, 2006
Design of potent, orally available antagonists of the transient receptor potential vanilloid 1. Structure-activity relationships of 2-piperazin-1-yl-1H-benzimidazolesVassil I Ognyanov, Chenera Balan, Anthony W Bannon, et al.Bioorganic & Medicinal Chemistry Letters|February 9, 2010
2-Aminothiadiazole inhibitors of AKT1 as potential cancer therapeuticsQingping Zeng, Matthew P Bourbeau, G Erich Wohlhieter, et al.Bioorganic & Medicinal Chemistry Letters|September 18, 2007
Discovery of N-phenyl nicotinamides as potent inhibitors of KdrCelia Dominguez, Leon Smith, Qi Huang, et al.Journal of Medicinal Chemistry|June 26, 2007
Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidateElizabeth M Doherty, Christopher Fotsch, Anthony W Bannon, et al.Nucleic Acids Research|July 4, 2025
Elucidation of multiple high-resolution states of human MutSβ by cryo-EM reveals interplay between ATP/ADP binding and heteroduplex DNA recognitionJung-Hoon Lee, Maren Thomsen, Herwin Daub, et al.Bioorganic & Medicinal Chemistry|September 10, 2011
Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitorsMichel C Maillard, Frederick A Brookfield, Stephen M Courtney, et al.Journal of Medicinal Chemistry|June 17, 2008
Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458)Longbin Liu, Aaron Siegmund, Ning Xi, et al.Pageof 9