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Bioorganic & Medicinal Chemistry Letters|February 9, 2010
Azole-based inhibitors of AKT/PKB for the treatment of cancerQingping Zeng, John G Allen, Matthew P Bourbeau, et al.Experimental Neurology|May 11, 2016
The novel KMO inhibitor CHDI-340246 leads to a restoration of electrophysiological alterations in mouse models of Huntington's diseaseVahri Beaumont, Ladislav Mrzljak, Ulrike Dijkman, et al.Journal of Medicinal Chemistry|September 13, 2022
Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington's Disease PathologyNatsuko Macabuag, William Esmieu, Perla Breccia, et al.Journal of Medicinal Chemistry|July 11, 2022
Identification of a Potent, Selective, and Brain-Penetrant Rho Kinase Inhibitor and its Activity in a Mouse Model of Huntington's DiseaseTammy Ladduwahetty, Matthew R Lee, Michel C Maillard, et al.Journal of Medicinal Chemistry|September 4, 2008
Design, synthesis, and biological evaluation of potent c-Met inhibitorsNoel D D'Angelo, Steven F Bellon, Shon K Booker, et al.Bioorganic & Medicinal Chemistry Letters|July 4, 2025
Orthosteric inhibition of MutSβ ATPase function: First disclosure of MSH3-bound small molecule inhibitorsGareth N Brace, Karsten Tillack, Peter D Johnson, et al.ACS Medicinal Chemistry Letters|March 19, 2021
Evaluation of 5-(Trifluoromethyl)-1,2,4-oxadiazole-Based Class IIa HDAC Inhibitors for Huntington's DiseaseAndrew J Stott, Michel C Maillard, Vahri Beaumont, et al.Science Translational Medicine|February 2, 2022
Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's diseaseDaniele Bertoglio, Jonathan Bard, Manuela Hessmann, et al.Scientific Reports|September 10, 2021
Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidatesFrank Herrmann, Manuela Hessmann, Sabine Schaertl, et al.Journal of Medicinal Chemistry|March 30, 2021
Structure-Based Exploration of Selectivity for ATM Inhibitors in Huntington's DiseaseAmanda Van de Poël, Leticia Toledo-Sherman, Perla Breccia, et al.Pageof 9