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Molecular Interventions
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July 14, 2009
Orthosteric/allosteric bitopic ligands: going hybrid at GPCRs
Celine Valant, Patrick M Sexton, Arthur Christopoulos
Molecular Pharmacology
|
September 15, 2018
Utility of an "Allosteric Site-Impaired" M<sub>2</sub> Muscarinic Acetylcholine Receptor as a Novel Construct for Validating Mechanisms of Action of Synthetic and Putative Endogenous Allosteric Modulators
Ee Von Moo, Patrick M Sexton, Arthur Christopoulos, et al.
Molecular Pharmacology
|
October 13, 2011
Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects
Celine Valant, Christian C Felder, Patrick M Sexton, et al.
Neuropharmacology
|
July 27, 2024
Ligand bias at the muscarinic acetylcholine receptor family: Opportunities and challenges
Michaela G Kaoullas, David M Thal, Arthur Christopoulos, et al.
Annual Review of Pharmacology and Toxicology
|
September 14, 2011
The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors
Celine Valant, J Robert Lane, Patrick M Sexton, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
February 5, 2015
Endogenous allosteric modulators of G protein-coupled receptors
Emma T van der Westhuizen, Celine Valant, Patrick M Sexton, et al.
British Journal of Pharmacology
|
December 24, 2022
Therapeutic potential of allosteric modulators for the treatment of gastrointestinal motility disorders
Ayame Saito, Sadia Alvi, Celine Valant, et al.
ACS Chemical Neuroscience
|
April 11, 2015
Synthesis and pharmacological evaluation of M4 muscarinic receptor positive allosteric modulators derived from VU10004
Tracey Huynh, Celine Valant, Ian T Crosby, et al.
Journal of Medicinal Chemistry
|
April 16, 2025
The Prosperity and Adversity of M<sub>4</sub> Muscarinic Acetylcholine Receptor Activators in the Treatment of Neuropsychiatric Disorders
Boqun Liu, Arthur Christopoulos, David M Thal, et al.
Journal of Medicinal Chemistry
|
October 1, 2013
Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptor
Tracey Huynh, Celine Valant, Ian T Crosby, et al.
Page
of 8
Search research articles
Search
Showing results (1-10 of 73) with videos related to
Sort By:
Page
of 8
Molecular Interventions
|
July 14, 2009
Orthosteric/allosteric bitopic ligands: going hybrid at GPCRs
Celine Valant, Patrick M Sexton, Arthur Christopoulos
Molecular Pharmacology
|
September 15, 2018
Utility of an "Allosteric Site-Impaired" M<sub>2</sub> Muscarinic Acetylcholine Receptor as a Novel Construct for Validating Mechanisms of Action of Synthetic and Putative Endogenous Allosteric Modulators
Ee Von Moo, Patrick M Sexton, Arthur Christopoulos, et al.
Molecular Pharmacology
|
October 13, 2011
Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects
Celine Valant, Christian C Felder, Patrick M Sexton, et al.
Neuropharmacology
|
July 27, 2024
Ligand bias at the muscarinic acetylcholine receptor family: Opportunities and challenges
Michaela G Kaoullas, David M Thal, Arthur Christopoulos, et al.
Annual Review of Pharmacology and Toxicology
|
September 14, 2011
The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptors
Celine Valant, J Robert Lane, Patrick M Sexton, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
February 5, 2015
Endogenous allosteric modulators of G protein-coupled receptors
Emma T van der Westhuizen, Celine Valant, Patrick M Sexton, et al.
British Journal of Pharmacology
|
December 24, 2022
Therapeutic potential of allosteric modulators for the treatment of gastrointestinal motility disorders
Ayame Saito, Sadia Alvi, Celine Valant, et al.
ACS Chemical Neuroscience
|
April 11, 2015
Synthesis and pharmacological evaluation of M4 muscarinic receptor positive allosteric modulators derived from VU10004
Tracey Huynh, Celine Valant, Ian T Crosby, et al.
Journal of Medicinal Chemistry
|
April 16, 2025
The Prosperity and Adversity of M<sub>4</sub> Muscarinic Acetylcholine Receptor Activators in the Treatment of Neuropsychiatric Disorders
Boqun Liu, Arthur Christopoulos, David M Thal, et al.
Journal of Medicinal Chemistry
|
October 1, 2013
Probing structural requirements of positive allosteric modulators of the M4 muscarinic receptor
Tracey Huynh, Celine Valant, Ian T Crosby, et al.
Page
of 8