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Celine Valant

Showing results (31-40 of 73) with videos related to

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Journal of Medicinal Chemistry|July 18, 2024
Discovery of 2-Methyl-5-(1<i>H</i>-pyrazol-4-yl)pyridines and Related Heterocycles as Promising M<sub>4</sub> mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive DisordersBoqun Liu, Geoff Thompson, Manuela Jörg, et al.
Journal of Medicinal Chemistry|February 10, 2012
Synthesis and characterization of novel 2-amino-3-benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A(1) receptorCeline Valant, Luigi Aurelio, Shane M Devine, et al.
Molecular Pharmacology|August 6, 2015
Label-Free Kinetics: Exploiting Functional Hemi-Equilibrium to Derive Rate Constants for Muscarinic Receptor AntagonistsDarren M Riddy, Celine Valant, Patricia Rueda, et al.
The Journal of Pharmacology and Experimental Therapeutics|July 31, 2009
Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivityGregory D Stewart, Celine Valant, Simon J Dowell, et al.
British Journal of Pharmacology|November 10, 2022
Opportunities and challenges for the development of M<sub>1</sub> muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficitsHuong T M Nguyen, Emma T van der Westhuizen, Christopher J Langmead, et al.
Biochemical Pharmacology|May 20, 2018
Probing the binding site of novel selective positive allosteric modulators at the M<sub>1</sub> muscarinic acetylcholine receptorElham Khajehali, Celine Valant, Manuela Jörg, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 13, 2014
Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonistCeline Valant, Lauren T May, Luigi Aurelio, et al.
Molecular Pharmacology|June 16, 2010
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screeningCassandra Koole, Denise Wootten, John Simms, et al.
Frontiers in Pharmacology|February 15, 2021
Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and BiasEmma T van der Westhuizen, K H Christopher Choy, Celine Valant, et al.
Journal of Medicinal Chemistry|September 6, 2008
2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonistsGemma N Ferguson, Celine Valant, James Horne, et al.
Pageof 8

Showing results (31-40 of 73) with videos related to

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Pageof 8
Journal of Medicinal Chemistry|July 18, 2024
Discovery of 2-Methyl-5-(1<i>H</i>-pyrazol-4-yl)pyridines and Related Heterocycles as Promising M<sub>4</sub> mAChR Positive Allosteric Modulators for the Treatment of Neurocognitive DisordersBoqun Liu, Geoff Thompson, Manuela Jörg, et al.
Journal of Medicinal Chemistry|February 10, 2012
Synthesis and characterization of novel 2-amino-3-benzoylthiophene derivatives as biased allosteric agonists and modulators of the adenosine A(1) receptorCeline Valant, Luigi Aurelio, Shane M Devine, et al.
Molecular Pharmacology|August 6, 2015
Label-Free Kinetics: Exploiting Functional Hemi-Equilibrium to Derive Rate Constants for Muscarinic Receptor AntagonistsDarren M Riddy, Celine Valant, Patricia Rueda, et al.
The Journal of Pharmacology and Experimental Therapeutics|July 31, 2009
Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivityGregory D Stewart, Celine Valant, Simon J Dowell, et al.
British Journal of Pharmacology|November 10, 2022
Opportunities and challenges for the development of M<sub>1</sub> muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficitsHuong T M Nguyen, Emma T van der Westhuizen, Christopher J Langmead, et al.
Biochemical Pharmacology|May 20, 2018
Probing the binding site of novel selective positive allosteric modulators at the M<sub>1</sub> muscarinic acetylcholine receptorElham Khajehali, Celine Valant, Manuela Jörg, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 13, 2014
Separation of on-target efficacy from adverse effects through rational design of a bitopic adenosine receptor agonistCeline Valant, Lauren T May, Luigi Aurelio, et al.
Molecular Pharmacology|June 16, 2010
Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screeningCassandra Koole, Denise Wootten, John Simms, et al.
Frontiers in Pharmacology|February 15, 2021
Fine Tuning Muscarinic Acetylcholine Receptor Signaling Through Allostery and BiasEmma T van der Westhuizen, K H Christopher Choy, Celine Valant, et al.
Journal of Medicinal Chemistry|September 6, 2008
2-aminothienopyridazines as novel adenosine A1 receptor allosteric modulators and antagonistsGemma N Ferguson, Celine Valant, James Horne, et al.
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