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Genetics in Medicine Open|December 13, 2024
Integration of validated functional evidence to support the pathogenicity of <i>KCNH2</i> variantsReema W Aljassar, Qianyi Shen, Buthaina Albash, et al.European Biophysics Journal : EBJ|April 19, 2005
The conformational flexibility of the antibiotic virginiamycin M(1)Jason Dang, Robert P Metzger, Robert T C Brownlee, et al.Plos One|November 9, 2013
C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channelsChai Ann Ng, Ying Ke, Matthew D Perry, et al.The Journal of Biological Chemistry|June 19, 2016
Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow DeactivationChai-Ann Ng, Andrée E Gravel, Matthew D Perry, et al.Plos One|February 24, 2012
The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gatingChai Ann Ng, Matthew D Perry, Peter S Tan, et al.Biochimica Et Biophysica Acta|April 20, 2007
The conformation of acetylated virginiamycin M1 and virginiamycin M1 in explicit solventsChai Ann Ng, Wen Zhao, Jason Dang, et al.The Journal of Biological Chemistry|March 11, 2017
The S1 helix critically regulates the finely tuned gating of Kv11.1 channelsKevin Phan, Chai Ann Ng, Erikka David, et al.The Biochemical Journal|June 1, 2013
Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactionsYing Ke, Chai Ann Ng, Mark J Hunter, et al.The Journal of Physiology|March 31, 2015
Getting to the heart of hERG K(+) channel gatingMatthew D Perry, Chai-Ann Ng, Stefan A Mann, et al.Biology Methods & Protocols|April 22, 2021
Heterozygous <i>KCNH2</i> variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiologyChai-Ann Ng, Jessica Farr, Paul Young, et al.Pageof 5