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Methods in Molecular Biology (Clifton, N.J.)|October 24, 2019
LC/MS Methods for Studying Lysosomal ADC CatabolismAndrew J Bessire, Chakrapani Subramanyam
Proteins|March 13, 2009
Structural comparison of chromosomal and exogenous dihydrofolate reductase from Staphylococcus aureus in complex with the potent inhibitor trimethoprimHolly Heaslet, Melissa Harris, Kelly Fahnoe, et al.
ACS Medicinal Chemistry Letters|August 16, 2019
Quick Building Blocks (QBB): An Innovative and Efficient Business Model To Speed Medicinal Chemistry Analog SynthesisChristopher J Helal, Mark Bundesmann, Susan Hammond, et al.
Bioconjugate Chemistry|May 22, 2016
Determination of Antibody-Drug Conjugate Released Payload Species Using Directed in Vitro Assays and Mass Spectrometric InterrogationAndrew J Bessire, T Eric Ballard, Manoj Charati, et al.
Bioorganic & Medicinal Chemistry Letters|July 26, 2011
Discovery, synthesis and SAR of azinyl- and azolylbenzamides antagonists of the P2X₇ receptorChakrapani Subramanyam, Allen J Duplantier, Mark A Dombroski, et al.
Plos One|May 31, 2017
Multivalent peptidic linker enables identification of preferred sites of conjugation for a potent thialanstatin antibody drug conjugateSujiet Puthenveetil, Haiyin He, Frank Loganzo, et al.
Cell Chemical Biology|November 20, 2018
Covalent Docking Identifies a Potent and Selective MKK7 InhibitorAmit Shraga, Evgenia Olshvang, Natalia Davidzohn, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 21, 2011
Quantitative pharmacokinetic/pharmacodynamic analyses suggest that the 129/SVE mouse is a suitable preclinical pharmacology model for identifying small-molecule γ-secretase inhibitorsYasong Lu, Liming Zhang, Charles E Nolan, et al.
ACS Chemical Neuroscience|June 14, 2017
Identification and Profiling of a Selective and Brain Penetrant Radioligand for in Vivo Target Occupancy Measurement of Casein Kinase 1 (CK1) InhibitorsTravis T Wager, Paul Galatsis, Ramalakshmi Y Chandrasekaran, et al.
ACS Medicinal Chemistry Letters|November 25, 2016
Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC PayloadsCarolyn A Leverett, Sai Chetan K Sukuru, Beth C Vetelino, et al.
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