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Bioorganic & Medicinal Chemistry Letters|October 2, 2007
Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2Kamil Paruch, Michael P Dwyer, Carmen Alvarez, et al.Journal of Medicinal Chemistry|April 21, 2007
Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimizationAndrew J Prongay, Zhuyan Guo, Nanhua Yao, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent KinasesKamil Paruch, Michael P Dwyer, Carmen Alvarez, et al.Journal of Synchrotron Radiation|April 19, 2008
Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034Vincent Madison, Andrew J Prongay, Zhuyan Guo, et al.Bioorganic & Medicinal Chemistry Letters|November 26, 2010
Novel TNF-α converting enzyme (TACE) inhibitors as potential treatment for inflammatory diseasesVinay M Girijavallabhan, Lei Chen, Chaoyang Dai, et al.Bioorganic & Medicinal Chemistry Letters|July 20, 2010
Structure and activity relationships of tartrate-based TACE inhibitorsDansu Li, Janeta Popovici-Muller, David B Belanger, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease InhibitorAshok Arasappan, Frank Bennett, Stephane L Bogen, et al.Bioorganic & Medicinal Chemistry Letters|December 22, 2009
The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitorsKristin E Rosner, Zhuyan Guo, Peter Orth, et al.Journal of Medicinal Chemistry|September 29, 2006
Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infectionSrikanth Venkatraman, Stéphane L Bogen, Ashok Arasappan, et al.Pageof 4