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Nature Communications|June 24, 2023
Schizophrenia-associated NRXN1 deletions induce developmental-timing- and cell-type-specific vulnerabilities in human brain organoidsRebecca Sebastian, Kang Jin, Narciso Pavon, et al.
Journal of Neurochemistry|December 1, 2025
Patient-Derived Variants Define Constraints for Ligand Binding at the PDZ Domain of CASKDebora Tibbe, Hans-Hinrich Hönck, Neha Bhatia, et al.
Stem Cell Reports|September 26, 2014
Generation of induced neuronal cells by the single reprogramming factor ASCL1Soham Chanda, Cheen Euong Ang, Jonathan Davila, et al.
Biorxiv : the Preprint Server for Biology|August 12, 2025
Distinct Synaptic Mechanisms Drive NRXN1 Variant-Mediated Pathogenesis in iPSC-Derived Neuronal Models of Autism and SchizophreniaJay English, Danny McSweeney, Jinghui Geng, et al.
Cell Reports|March 22, 2026
Distinct synaptic mechanisms underlie NRXN1 variant and disorder background-dependent phenotypes in iPSC-derived neuronsJay English, Danny McSweeney, Jinghui Geng, et al.
Neuron|June 15, 2013
Rapid single-step induction of functional neurons from human pluripotent stem cellsYingsha Zhang, Changhui Pak, Yan Han, et al.
Human Genetics|March 6, 2023
oFlowSeq: a quantitative approach to identify protein coding mutations affecting cell type enrichment using mosaic CRISPR-Cas9 edited cerebral organoidsPepper Dawes, Liam F Murray, Meagan N Olson, et al.
Molecular Psychiatry|October 25, 2022
Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanismLe Wang, Vincent R Mirabella, Rujia Dai, et al.
Cell Reports|August 10, 2017
The Conserved, Disease-Associated RNA Binding Protein dNab2 Interacts with the Fragile X Protein Ortholog in Drosophila NeuronsRick S Bienkowski, Ayan Banerjee, J Christopher Rounds, et al.
Proceedings of the National Academy of Sciences of the United States of America|May 26, 2021
Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived NRXN1-mutant neuronsChangHui Pak, Tamas Danko, Vincent R Mirabella, et al.
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