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Nature Biotechnology|June 3, 2025
A mitochondrial disease model is generated and corrected using engineered base editors in rat zygotesLiang Chen, Changming Luan, Mengjia Hong, et al.
Nature Biotechnology|June 3, 2025
Efficient mitochondrial A-to-G base editors for the generation of mitochondrial disease modelsLiang Chen, Mengjia Hong, Changming Luan, et al.
Nature Biotechnology|June 15, 2023
Adenine transversion editors enable precise, efficient A•T-to-C•G base editing in mammalian cells and embryosLiang Chen, Mengjia Hong, Changming Luan, et al.
Nature Chemical Biology|October 13, 2022
Engineering a precise adenine base editor with minimal bystander editingLiang Chen, Shun Zhang, Niannian Xue, et al.
Nature Biotechnology|November 11, 2022
Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editingLiang Chen, Biyun Zhu, Gaomeng Ru, et al.
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