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The Journal of Antibiotics|June 24, 2021
Natural products targeting cancer cell dependencyChangxiang Shi, Eun Ju Yang, Shishi Tao, et al.
Experimental & Molecular Medicine|May 29, 2021
Aurora kinase A, a synthetic lethal target for precision cancer medicinePui Kei Mou, Eun Ju Yang, Changxiang Shi, et al.
Oncogene|December 9, 2020
Bromodomain and extra-terminal motif (BET) inhibition is synthetic lethal with loss of SMAD4 in colorectal cancer cells via restoring the loss of MYC repressionChangxiang Shi, Eun Ju Yang, Yifan Liu, et al.
International Journal of Biological Sciences|May 14, 2020
Histone Acetyltransferase (HAT) P300/CBP Inhibitors Induce Synthetic Lethality in PTEN-Deficient Colorectal Cancer Cells through Destabilizing AKTYifan Liu, Eun Ju Yang, Changxiang Shi, et al.
Experimental & Molecular Medicine|January 6, 2025
Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repairShishi Tao, Yue Pu, Eun Ju Yang, et al.
Iscience|February 26, 2026
Serum metabolic fingerprinting for diagnosis and therapeutic applications of ovarian endometriosisChencheng Dai, Yiwei Cao, Yiran Xu, et al.
Oncogene|April 8, 2022
Aurora kinase A inhibition induces synthetic lethality in SMAD4-deficient colorectal cancer cells via spindle assembly checkpoint activationChangxiang Shi, Shishi Tao, Guowen Ren, et al.
Nature Communications|October 10, 2020
Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamicsJunfang Lyu, Eun Ju Yang, Baoyuan Zhang, et al.
International Journal of Biological Sciences|March 9, 2026
ARID1A deficiency activates OSM-STAT3 axis in endometrial cancer, creating vulnerability to JAK/STAT3 inhibitionLi-Jie Chen, Changxiang Shi, Eun Ju Yang, et al.
Cancer Research|May 25, 2023
BRCA1 Insufficiency Induces a Hypersialylated Acidic Tumor Microenvironment That Promotes Metastasis and Immunotherapy ResistanceXiaodong Shu, Jianjie Li, Un In Chan, et al.
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