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Expert Opinion on Therapeutic Targets|November 23, 2005
Phosphodiesterase-4 as a potential drug targetKam Y J Zhang, Prabha N Ibrahim, Sam Gillette, et al.
Haematologica|January 28, 2021
A novel combination regimen of BET and FLT3 inhibition for FLT3-ITD acute myeloid leukemiaLauren Lee, Yoshiyuki Hizukuri, Paul Severson, et al.
Nature Communications|February 9, 2016
KRAS insertion mutations are oncogenic and exhibit distinct functional propertiesYasmine White, Aditi Bagchi, Jessica Van Ziffle, et al.
Neoplasia (New York, N.Y.)|August 7, 2010
Pharmacodynamic characterization of the efficacy signals due to selective BRAF inhibition with PLX4032 in malignant melanomaWilliam D Tap, Ke-Wei Gong, Judy Dering, et al.
Cell Cycle (Georgetown, Tex.)|August 22, 2006
Germline mutations in components of the Ras signaling pathway in Noonan syndrome and related disordersChristian P Kratz, Suzanne Schubbert, Gideon Bollag, et al.
JCI Insight|September 8, 2023
Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activationPan-Yu Chen, Benjamin J Huang, Max Harris, et al.
Cancer Cell|August 16, 2016
An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF SignalingZoi Karoulia, Yang Wu, Tamer A Ahmed, et al.
Clinical and Experimental Medicine|December 8, 2018
PLX9486 shows anti-tumor efficacy in patient-derived, tyrosine kinase inhibitor-resistant KIT-mutant xenograft models of gastrointestinal stromal tumorsYemarshet K Gebreyohannes, Elizabeth A Burton, Agnieszka Wozniak, et al.
Oncoimmunology|May 4, 2016
Co-inhibition of colony stimulating factor-1 receptor and BRAF oncogene in mouse models of BRAFV600E melanomaShin Foong Ngiow, Katrina M Meeth, Kimberley Stannard, et al.
Cancer Research|February 19, 2013
CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancerJingying Xu, Jemima Escamilla, Stephen Mok, et al.
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