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Journal of Medicinal Chemistry
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May 19, 2026
Discovery of Fosigotifator, a Potent eIF2B Activator with Desired Properties for Human Studies
Jennifer M Frost, Yunsong Tong, Xiangdong Xu, et al.
Journal of Medicinal Chemistry
|
June 9, 2006
Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity
Bruce G Szczepankiewicz, Christi Kosogof, Lissa T J Nelson, et al.
Communications Chemistry
|
August 16, 2024
Mechanistic insights into a heterobifunctional degrader-induced PTPN2/N1 complex
Qi Hao, Manoj K Rathinaswamy, Kelly L Klinge, et al.
Journal of Medicinal Chemistry
|
May 2, 2015
Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity
Milan Bruncko, Le Wang, George S Sheppard, et al.
Journal of Medicinal Chemistry
|
February 14, 2015
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity
Milan Bruncko, Le Wang, George S Sheppard, et al.
Journal of Medicinal Chemistry
|
December 30, 2020
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design
Justin D Dietrich, Kenton L Longenecker, Noel S Wilson, et al.
Journal of Medicinal Chemistry
|
March 6, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>
John T Randolph, Matthew J O'Connor, Fei Han, et al.
Journal of Medicinal Chemistry
|
June 5, 2025
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen
Yunsong Tong, Kenton A Baker, Alex M Chapman, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 8, 2017
Methylpyrrole inhibitors of BET bromodomains
Lisa A Hasvold, George S Sheppard, Le Wang, et al.
ACS Chemical Biology
|
November 25, 2010
Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases
Kenneth M Comess, Chaohong Sun, Cele Abad-Zapatero, et al.
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of 6
Search research articles
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Showing results (41-50 of 58) with videos related to
Sort By:
Page
of 6
Journal of Medicinal Chemistry
|
May 19, 2026
Discovery of Fosigotifator, a Potent eIF2B Activator with Desired Properties for Human Studies
Jennifer M Frost, Yunsong Tong, Xiangdong Xu, et al.
Journal of Medicinal Chemistry
|
June 9, 2006
Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity
Bruce G Szczepankiewicz, Christi Kosogof, Lissa T J Nelson, et al.
Communications Chemistry
|
August 16, 2024
Mechanistic insights into a heterobifunctional degrader-induced PTPN2/N1 complex
Qi Hao, Manoj K Rathinaswamy, Kelly L Klinge, et al.
Journal of Medicinal Chemistry
|
May 2, 2015
Correction to Structure-Guided Design of a Series of MCL-1 Inhibitors with High Affinity and Selectivity
Milan Bruncko, Le Wang, George S Sheppard, et al.
Journal of Medicinal Chemistry
|
February 14, 2015
Structure-guided design of a series of MCL-1 inhibitors with high affinity and selectivity
Milan Bruncko, Le Wang, George S Sheppard, et al.
Journal of Medicinal Chemistry
|
December 30, 2020
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design
Justin D Dietrich, Kenton L Longenecker, Noel S Wilson, et al.
Journal of Medicinal Chemistry
|
March 6, 2023
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis <i>In Vivo</i>
John T Randolph, Matthew J O'Connor, Fei Han, et al.
Journal of Medicinal Chemistry
|
June 5, 2025
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen
Yunsong Tong, Kenton A Baker, Alex M Chapman, et al.
Bioorganic & Medicinal Chemistry Letters
|
March 8, 2017
Methylpyrrole inhibitors of BET bromodomains
Lisa A Hasvold, George S Sheppard, Le Wang, et al.
ACS Chemical Biology
|
November 25, 2010
Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases
Kenneth M Comess, Chaohong Sun, Cele Abad-Zapatero, et al.
Page
of 6