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June 19, 2013
Generation and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgG
Xiangdan Wang, Valerie Quarmby, Carl Ng, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 20, 2019
Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group
Gregory L Hamilton, Huifen Chen, Gauri Deshmukh, et al.
Nature Structural & Molecular Biology
|
August 22, 2017
Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists
Yingnan Zhang, Mark Ultsch, Nicholas J Skelton, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 8, 2015
4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase
Emily J Hanan, Matt Baumgardner, Marian C Bryan, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 4, 2014
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 18, 2013
Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors
Sharada Labadie, Kathy Barrett, Wade S Blair, et al.
The Journal of Biological Chemistry
|
January 6, 2005
A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo
Alan G Olivero, Charles Eigenbrot, Richard Goldsmith, et al.
Journal of Molecular Biology
|
March 6, 2013
Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies
Homer Pantua, Jingyu Diao, Mark Ultsch, et al.
Nature Communications
|
December 23, 2020
Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge
Henry R Maun, Rajesh Vij, Benjamin T Walters, et al.
ACS Medicinal Chemistry Letters
|
August 25, 2020
Stereochemical Differences in Fluorocyclopropyl Amides Enable Tuning of Btk Inhibition and Off-Target Activity
James J Crawford, Wendy Lee, Adam R Johnson, et al.
Page
of 11
Search research articles
Search
Showing results (51-60 of 102) with videos related to
Sort By:
Page
of 11
Mabs
|
June 19, 2013
Generation and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgG
Xiangdan Wang, Valerie Quarmby, Carl Ng, et al.
Bioorganic & Medicinal Chemistry Letters
|
April 20, 2019
Potent and selective inhibitors of receptor-interacting protein kinase 1 that lack an aromatic back pocket group
Gregory L Hamilton, Huifen Chen, Gauri Deshmukh, et al.
Nature Structural & Molecular Biology
|
August 22, 2017
Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists
Yingnan Zhang, Mark Ultsch, Nicholas J Skelton, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 8, 2015
4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase
Emily J Hanan, Matt Baumgardner, Marian C Bryan, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 4, 2014
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase
Benjamin P Fauber, Peter S Dragovich, Jinhua Chen, et al.
Bioorganic & Medicinal Chemistry Letters
|
September 18, 2013
Design and evaluation of novel 8-oxo-pyridopyrimidine Jak1/2 inhibitors
Sharada Labadie, Kathy Barrett, Wade S Blair, et al.
The Journal of Biological Chemistry
|
January 6, 2005
A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo
Alan G Olivero, Charles Eigenbrot, Richard Goldsmith, et al.
Journal of Molecular Biology
|
March 6, 2013
Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies
Homer Pantua, Jingyu Diao, Mark Ultsch, et al.
Nature Communications
|
December 23, 2020
Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge
Henry R Maun, Rajesh Vij, Benjamin T Walters, et al.
ACS Medicinal Chemistry Letters
|
August 25, 2020
Stereochemical Differences in Fluorocyclopropyl Amides Enable Tuning of Btk Inhibition and Off-Target Activity
James J Crawford, Wendy Lee, Adam R Johnson, et al.
Page
of 11