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Bioorganic & Medicinal Chemistry Letters
|
January 22, 2022
Structure-based optimization of hydroxylactam as potent, cell-active inhibitors of lactate dehydrogenase
BinQing Wei, Kirk Robarge, Sharada S Labadie, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2013
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)
Colin H MacKinnon, Kevin Lau, Jason D Burch, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 24, 2017
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
Jun Liang, Anne Van Abbema, Mercedesz Balazs, et al.
Journal of Medicinal Chemistry
|
May 18, 2012
Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors
Janusz J Kulagowski, Wade Blair, Richard J Bull, et al.
Journal of Medicinal Chemistry
|
January 8, 2016
The Rational Design of Selective Benzoxazepin Inhibitors of the α-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326)
Timothy P Heffron, Robert A Heald, Chudi Ndubaku, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 20, 2014
Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase
Peter S Dragovich, Benjamin P Fauber, Jason Boggs, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 18, 2015
Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability
Wendy B Young, James Barbosa, Peter Blomgren, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K)
Georgette M Castanedo, Nicole Blaquiere, Maureen Beresini, et al.
European Journal of Medicinal Chemistry
|
July 23, 2013
Lead identification of novel and selective TYK2 inhibitors
Jun Liang, Vickie Tsui, Anne Van Abbema, et al.
Cancer Cell
|
May 18, 2013
Oncogenic ERBB3 mutations in human cancers
Bijay S Jaiswal, Noelyn M Kljavin, Eric W Stawiski, et al.
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Search research articles
Search
Showing results (81-90 of 102) with videos related to
Sort By:
Page
of 11
Bioorganic & Medicinal Chemistry Letters
|
January 22, 2022
Structure-based optimization of hydroxylactam as potent, cell-active inhibitors of lactate dehydrogenase
BinQing Wei, Kirk Robarge, Sharada S Labadie, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 22, 2013
Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK)
Colin H MacKinnon, Kevin Lau, Jason D Burch, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 24, 2017
Identification of an imidazopyridine scaffold to generate potent and selective TYK2 inhibitors that demonstrate activity in an in vivo psoriasis model
Jun Liang, Anne Van Abbema, Mercedesz Balazs, et al.
Journal of Medicinal Chemistry
|
May 18, 2012
Identification of imidazo-pyrrolopyridines as novel and potent JAK1 inhibitors
Janusz J Kulagowski, Wade Blair, Richard J Bull, et al.
Journal of Medicinal Chemistry
|
January 8, 2016
The Rational Design of Selective Benzoxazepin Inhibitors of the α-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326)
Timothy P Heffron, Robert A Heald, Chudi Ndubaku, et al.
Bioorganic & Medicinal Chemistry Letters
|
July 20, 2014
Identification of substituted 3-hydroxy-2-mercaptocyclohex-2-enones as potent inhibitors of human lactate dehydrogenase
Peter S Dragovich, Benjamin P Fauber, Jason Boggs, et al.
Bioorganic & Medicinal Chemistry Letters
|
December 18, 2015
Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability
Wendy B Young, James Barbosa, Peter Blomgren, et al.
Journal of Medicinal Chemistry
|
December 23, 2016
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K)
Georgette M Castanedo, Nicole Blaquiere, Maureen Beresini, et al.
European Journal of Medicinal Chemistry
|
July 23, 2013
Lead identification of novel and selective TYK2 inhibitors
Jun Liang, Vickie Tsui, Anne Van Abbema, et al.
Cancer Cell
|
May 18, 2013
Oncogenic ERBB3 mutations in human cancers
Bijay S Jaiswal, Noelyn M Kljavin, Eric W Stawiski, et al.
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of 11