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Brain Research|December 25, 2017
The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slicesElena Dale, Morten Grunnet, Alan L Pehrson, et al.Chemmedchem|May 23, 2014
Ergoline-derived inverse agonists of the human h3 receptor for the treatment of narcolepsyYves P Auberson, Thomas Troxler, Xuechun Zhang, et al.Chemmedchem|November 14, 2014
From ergolines to indoles: improved inhibitors of the human H3 receptor for the treatment of narcolepsyYves P Auberson, Thomas Troxler, Xuechun Zhang, et al.Molecular Pharmacology|August 17, 2018
Intracellular Binding Site for a Positive Allosteric Modulator of the Dopamine D1 ReceptorXushan Wang, Beverly A Heinz, Yue-Wei Qian, et al.Neuropharmacology|November 6, 2017
Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disordersRobert F Bruns, Stephen N Mitchell, Keith A Wafford, et al.The Journal of Pharmacology and Experimental Therapeutics|November 5, 2016
An Allosteric Potentiator of the Dopamine D1 Receptor Increases Locomotor Activity in Human D1 Knock-In Mice without Causing Stereotypy or TachyphylaxisKjell A Svensson, Beverly A Heinz, John M Schaus, et al.Journal of Medicinal Chemistry|September 19, 2019
Synthesis and Pharmacological Characterization of 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one (LY3154207), a Potent, Subtype Selective, and Orally Available Positive Allosteric Modulator of the Human Dopamine D1 ReceptorJunliang Hao, James P Beck, John M Schaus, et al.Pageof 3