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Antimicrobial Agents and Chemotherapy|April 22, 2015
Treatment with the smallpox antiviral tecovirimat (ST-246) alone or in combination with ACAM2000 vaccination is effective as a postsymptomatic therapy for monkeypox virus infectionAklile Berhanu, Jonathan T Prigge, Peter M Silvera, et al.Antimicrobial Agents and Chemotherapy|December 17, 2008
In vitro efficacy of ST246 against smallpox and monkeypoxScott K Smith, Victoria A Olson, Kevin L Karem, et al.Vaccine|November 2, 2010
Impact of ST-246® on ACAM2000™ smallpox vaccine reactogenicity, immunogenicity, and protective efficacy in immunodeficient miceAklile Berhanu, David S King, Stacie Mosier, et al.Antimicrobial Agents and Chemotherapy|September 16, 2009
ST-246 inhibits in vivo poxvirus dissemination, virus shedding, and systemic disease manifestationAklile Berhanu, David S King, Stacie Mosier, et al.Antimicrobial Agents and Chemotherapy|April 30, 2014
The broad-spectrum antiviral compound ST-669 restricts chlamydial inclusion development and bacterial growth and localizes to host cell lipid droplets within treated cellsKelsi M Sandoz, William G Valiant, Steven G Eriksen, et al.Journal of Virology|August 22, 2008
Identification of a broad-spectrum arenavirus entry inhibitorRyan A Larson, Dongcheng Dai, Virginia T Hosack, et al.Antiviral Research|May 16, 2008
Evaluation of orally delivered ST-246 as postexposure prophylactic and antiviral therapeutic in an aerosolized rabbitpox rabbit modelAysegul Nalca, Josh M Hatkin, Nicole L Garza, et al.Infection and Immunity|March 24, 2005
Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcus vaccineKaren L Kotloff, Steven S Wasserman, Kevin F Jones, et al.Antimicrobial Agents and Chemotherapy|November 23, 2006
Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in miceDebra C Quenelle, R M L Buller, Scott Parker, et al.The Journal of Antimicrobial Chemotherapy|January 30, 2015
ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrappingSophie Duraffour, María M Lorenzo, Gudrun Zöller, et al.Pageof 9