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Nature Communications|December 2, 2021
Tumor evolution selectively inactivates the core microRNA machinery for immune evasionTian-Yu Song, Min Long, Hai-Xin Zhao, et al.Autophagy|December 11, 2025
Cerebral FURIN deficiency impairs astrocytic lipophagy through ITGAV maturationXiao-Yong Xie, Lu Wang, Shi-Qi Xie, et al.Journal of Medicinal Chemistry|April 6, 2026
Discovery of AMG 133, a Glucose-Dependent Insulinotropic Polypeptide Receptor Antagonist and Glucagon-Like Peptide 1 Receptor Agonist Antibody-Drug Conjugate for the Treatment of ObesityBin Wu, James R Falsey, Chawita Netirojjanakul, et al.Medrxiv : the Preprint Server for Health Sciences|February 6, 2026
A Randomized Double-Blind Placebo-Controlled Phase I/II Clinical Trial of a Human Papillomavirus Therapeutic Vaccine, PepCan, for Reducing Head and Neck Cancer RecurrenceEmily Bivens, Omar Atiq, Teresa Evans, et al.Nature Metabolism|February 5, 2024
A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settingsMurielle M Véniant, Shu-Chen Lu, Larissa Atangan, et al.Autophagy|April 23, 2021
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influxJiansong Qi, Yanhong Xing, Yucheng Liu, et al.Nature Metabolism|April 29, 2025
GIPR-Ab/GLP-1 peptide-antibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese miceClarissa M Liu, Elizabeth A Killion, Rola Hammoud, et al.Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology|August 16, 2017
Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II-Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3Yong-Chen Lu, Linda L Parker, Tangying Lu, et al.Nature Genetics|November 8, 2016
Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinomaJia-Jie Hao, De-Chen Lin, Huy Q Dinh, et al.Journal of Medicinal Chemistry|June 26, 2015
Discovery and Modification of in Vivo Active Nrf2 Activators with 1,2,4-Oxadiazole Core: Hits Identification and Structure-Activity Relationship StudyLi-Li Xu, Jun-Feng Zhu, Xiao-Li Xu, et al.Pageof 130