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Science Signaling
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March 22, 2018
Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner
Hong Zheng, Wen-Mei Yu, Ronald R Waclaw, et al.
Journal of Medicinal Chemistry
|
August 21, 2013
Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11)
Wei Liu, Bing Yu, Gang Xu, et al.
The Journal of Experimental Medicine
|
September 21, 2011
Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells
Dan Xu, Xia Liu, Wen-Mei Yu, et al.
Leukemia Research
|
October 27, 2016
Synergistic cell death in FLT3-ITD positive acute myeloid leukemia by combined treatment with metformin and 6-benzylthioinosine
Himalee S Sabnis, Heath L Bradley, Shweta Tripathi, et al.
Molecular and Cellular Biology
|
October 12, 2011
A critical role of mitochondrial phosphatase Ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells
Jinhua Shen, Xia Liu, Wen-Mei Yu, et al.
Blood Advances
|
September 23, 2021
JMML tumor cells disrupt normal hematopoietic stem cells by imposing inflammatory stress through overproduction of IL-1β
Yuhan Yan, Lei Dong, Chao Chen, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 13, 2016
Gain-of-function mutations of Ptpn11 (Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignancies
Xia Liu, Hong Zheng, Xiaobo Li, et al.
Molecular and Cellular Biology
|
April 25, 2002
Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction
Randy Shen, Ying-Bin Ouyang, Cheng-Kui Qu, et al.
Blood
|
July 24, 2010
A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells
Dan Xu, Siying Wang, Wen-Mei Yu, et al.
Cellular Signalling
|
June 13, 2006
Shp-2 tyrosine phosphatase is required for hepatocyte growth factor-induced activation of sphingosine kinase and migration in embryonic fibroblasts
Hai-Feng Duan, Cheng-Kui Qu, Qun-Wei Zhang, et al.
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of 9
Search research articles
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Showing results (41-50 of 89) with videos related to
Sort By:
Page
of 9
Science Signaling
|
March 22, 2018
Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner
Hong Zheng, Wen-Mei Yu, Ronald R Waclaw, et al.
Journal of Medicinal Chemistry
|
August 21, 2013
Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11)
Wei Liu, Bing Yu, Gang Xu, et al.
The Journal of Experimental Medicine
|
September 21, 2011
Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells
Dan Xu, Xia Liu, Wen-Mei Yu, et al.
Leukemia Research
|
October 27, 2016
Synergistic cell death in FLT3-ITD positive acute myeloid leukemia by combined treatment with metformin and 6-benzylthioinosine
Himalee S Sabnis, Heath L Bradley, Shweta Tripathi, et al.
Molecular and Cellular Biology
|
October 12, 2011
A critical role of mitochondrial phosphatase Ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells
Jinhua Shen, Xia Liu, Wen-Mei Yu, et al.
Blood Advances
|
September 23, 2021
JMML tumor cells disrupt normal hematopoietic stem cells by imposing inflammatory stress through overproduction of IL-1β
Yuhan Yan, Lei Dong, Chao Chen, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
January 13, 2016
Gain-of-function mutations of Ptpn11 (Shp2) cause aberrant mitosis and increase susceptibility to DNA damage-induced malignancies
Xia Liu, Hong Zheng, Xiaobo Li, et al.
Molecular and Cellular Biology
|
April 25, 2002
Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction
Randy Shen, Ying-Bin Ouyang, Cheng-Kui Qu, et al.
Blood
|
July 24, 2010
A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells
Dan Xu, Siying Wang, Wen-Mei Yu, et al.
Cellular Signalling
|
June 13, 2006
Shp-2 tyrosine phosphatase is required for hepatocyte growth factor-induced activation of sphingosine kinase and migration in embryonic fibroblasts
Hai-Feng Duan, Cheng-Kui Qu, Qun-Wei Zhang, et al.
Page
of 9