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The EMBO Journal|February 20, 2010
A polycystin-2 (TRPP2) dimerization domain essential for the function of heteromeric polycystin complexesAurélie Giamarchi, Shuang Feng, Lise Rodat-Despoix, et al.
Lancet (London, England)|July 5, 2003
Association of mutation position in polycystic kidney disease 1 (PKD1) gene and development of a vascular phenotypeSandro Rossetti, Dominique Chauveau, Vickie Kubly, et al.
American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation|December 19, 2022
Venglustat, a Novel Glucosylceramide Synthase Inhibitor, in Patients at Risk of Rapidly Progressing ADPKD: Primary Results of a Double-Blind, Placebo-Controlled, Phase 2/3 Randomized Clinical TrialRonald T Gansevoort, Ali Hariri, Pascal Minini, et al.
Elife|February 12, 2026
BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKDUyen Tran, Andrew J Streets, Devon Smith, et al.
The Journal of Gene Medicine|February 26, 2024
Global analysis of urinary extracellular vesicle small RNAs in autosomal dominant polycystic kidney diseaseHamad Ali, Md Zubbair Malik, Mohamed Abu-Farha, et al.
Pflugers Archiv : European Journal of Physiology|November 7, 2013
Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metforminDjalila Mekahli, Jean-Paul Decuypere, Eva Sammels, et al.
Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association|August 29, 2014
Building a network of ADPKD reference centres across Europe: the EuroCYST initiativeKatja Petzold, Ron T Gansevoort, Albert C M Ong, et al.
Communications Medicine|April 19, 2025
Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathiesClaire E L Smith, Andrew J Streets, Alice V R Lake, et al.
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