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Journal of Medicinal Chemistry
|
January 1, 2008
Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator
Martyn Frederickson, Owen Callaghan, Gianni Chessari, et al.
Journal of Medicinal Chemistry
|
February 17, 2006
Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors
Nigel Howard, Chris Abell, Wendy Blakemore, et al.
Cell Death & Disease
|
July 23, 2013
SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma
N Crawford, I Stasik, C Holohan, et al.
Journal of Medicinal Chemistry
|
September 14, 2022
X-ray Screening of an Electrophilic Fragment Library and Application toward the Development of a Novel ERK 1/2 Covalent Inhibitor
Jeffrey D St Denis, Gianni Chessari, Anne Cleasby, et al.
Journal of Medicinal Chemistry
|
February 24, 2007
Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase
Miles Congreve, David Aharony, Jeffrey Albert, et al.
Journal of Medicinal Chemistry
|
October 3, 2003
Trisubstituted acridine derivatives as potent and selective telomerase inhibitors
R John Harrison, Javier Cuesta, Gianni Chessari, et al.
Nature Chemical Biology
|
October 2, 2012
Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
Susanne M Saalau-Bethell, Andrew J Woodhead, Gianni Chessari, et al.
Molecular Cancer Therapeutics
|
April 27, 2018
ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth
George A Ward, Edward J Lewis, Jong Sook Ahn, et al.
Journal of Medicinal Chemistry
|
August 20, 2010
Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency
Christopher W Murray, Maria G Carr, Owen Callaghan, et al.
Oncotarget
|
January 23, 2016
PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy
Chris W D Armstrong, Pamela J Maxwell, Chee Wee Ong, et al.
Page
of 8
Search research articles
Search
Showing results (51-60 of 72) with videos related to
Sort By:
Page
of 8
Journal of Medicinal Chemistry
|
January 1, 2008
Fragment-based discovery of mexiletine derivatives as orally bioavailable inhibitors of urokinase-type plasminogen activator
Martyn Frederickson, Owen Callaghan, Gianni Chessari, et al.
Journal of Medicinal Chemistry
|
February 17, 2006
Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors
Nigel Howard, Chris Abell, Wendy Blakemore, et al.
Cell Death & Disease
|
July 23, 2013
SAHA overcomes FLIP-mediated inhibition of SMAC mimetic-induced apoptosis in mesothelioma
N Crawford, I Stasik, C Holohan, et al.
Journal of Medicinal Chemistry
|
September 14, 2022
X-ray Screening of an Electrophilic Fragment Library and Application toward the Development of a Novel ERK 1/2 Covalent Inhibitor
Jeffrey D St Denis, Gianni Chessari, Anne Cleasby, et al.
Journal of Medicinal Chemistry
|
February 24, 2007
Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase
Miles Congreve, David Aharony, Jeffrey Albert, et al.
Journal of Medicinal Chemistry
|
October 3, 2003
Trisubstituted acridine derivatives as potent and selective telomerase inhibitors
R John Harrison, Javier Cuesta, Gianni Chessari, et al.
Nature Chemical Biology
|
October 2, 2012
Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function
Susanne M Saalau-Bethell, Andrew J Woodhead, Gianni Chessari, et al.
Molecular Cancer Therapeutics
|
April 27, 2018
ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth
George A Ward, Edward J Lewis, Jong Sook Ahn, et al.
Journal of Medicinal Chemistry
|
August 20, 2010
Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency
Christopher W Murray, Maria G Carr, Owen Callaghan, et al.
Oncotarget
|
January 23, 2016
PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy
Chris W D Armstrong, Pamela J Maxwell, Chee Wee Ong, et al.
Page
of 8