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Journal of Animal Science
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June 14, 2024
Analysis of ddRAD-seq data provides new insights into the genomic structure and patterns of diversity in Italian donkey populations
Andrea Criscione, Giorgio Chessari, Alberto Cesarani, et al.
Journal of Medicinal Chemistry
|
May 12, 2017
Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)
Emiliano Tamanini, Ildiko M Buck, Gianni Chessari, et al.
Journal of Medicinal Chemistry
|
November 8, 2007
Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency
Philip D Edwards, Jeffrey S Albert, Mark Sylvester, et al.
Journal of Medicinal Chemistry
|
July 29, 2015
Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP
Gianni Chessari, Ildiko M Buck, James E H Day, et al.
Journal of Medicinal Chemistry
|
August 10, 2018
A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660)
Christopher N Johnson, Jong Sook Ahn, Ildiko M Buck, et al.
ERJ Open Research
|
March 19, 2024
Diagnostic delay in bronchiectasis: an Italian perspective
Carlo Chessari, Edoardo Simonetta, Francesco Amati, et al.
Journal of Medicinal Chemistry
|
July 29, 2010
Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug design
Andrew J Woodhead, Hayley Angove, Maria G Carr, et al.
Journal of Medicinal Chemistry
|
June 27, 2024
Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase
Nick Palmer, Christopher Agnew, Caroline Benn, et al.
Journal of Medicinal Chemistry
|
April 9, 2026
From KRAS<sup><i>G12D</i></sup> to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design
Xiaoshen Ma, David L Sloman, Timothy J Henderson, et al.
Journal of Medicinal Chemistry
|
March 24, 2021
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction
Gianni Chessari, Ian R Hardcastle, Jong Sook Ahn, et al.
Page
of 8
Search research articles
Search
Showing results (61-70 of 72) with videos related to
Sort By:
Page
of 8
Journal of Animal Science
|
June 14, 2024
Analysis of ddRAD-seq data provides new insights into the genomic structure and patterns of diversity in Italian donkey populations
Andrea Criscione, Giorgio Chessari, Alberto Cesarani, et al.
Journal of Medicinal Chemistry
|
May 12, 2017
Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)
Emiliano Tamanini, Ildiko M Buck, Gianni Chessari, et al.
Journal of Medicinal Chemistry
|
November 8, 2007
Application of fragment-based lead generation to the discovery of novel, cyclic amidine beta-secretase inhibitors with nanomolar potency, cellular activity, and high ligand efficiency
Philip D Edwards, Jeffrey S Albert, Mark Sylvester, et al.
Journal of Medicinal Chemistry
|
July 29, 2015
Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP
Gianni Chessari, Ildiko M Buck, James E H Day, et al.
Journal of Medicinal Chemistry
|
August 10, 2018
A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660)
Christopher N Johnson, Jong Sook Ahn, Ildiko M Buck, et al.
ERJ Open Research
|
March 19, 2024
Diagnostic delay in bronchiectasis: an Italian perspective
Carlo Chessari, Edoardo Simonetta, Francesco Amati, et al.
Journal of Medicinal Chemistry
|
July 29, 2010
Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug design
Andrew J Woodhead, Hayley Angove, Maria G Carr, et al.
Journal of Medicinal Chemistry
|
June 27, 2024
Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase
Nick Palmer, Christopher Agnew, Caroline Benn, et al.
Journal of Medicinal Chemistry
|
April 9, 2026
From KRAS<sup><i>G12D</i></sup> to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design
Xiaoshen Ma, David L Sloman, Timothy J Henderson, et al.
Journal of Medicinal Chemistry
|
March 24, 2021
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction
Gianni Chessari, Ian R Hardcastle, Jong Sook Ahn, et al.
Page
of 8