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Translational Neurodegeneration|February 14, 2022
LRRK2 mutant knock-in mouse models: therapeutic relevance in Parkinson's diseaseEunice Eun Seo Chang, Philip Wing-Lok Ho, Hui-Fang Liu, et al.
Chemical Science|July 13, 2018
Identification of "sarsasapogenin-aglyconed" timosaponins as novel Aβ-lowering modulators of amyloid precursor protein processingLai-King Sy, Chun-Nam Lok, Juan-Yu Wang, et al.
Scientific Reports|January 19, 2017
Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson's diseaseHui-Fang Liu, Philip Wing-Lok Ho, Gideon Chi-Ting Leung, et al.
Autophagy|April 16, 2019
Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)Philip Wing-Lok Ho, Chi-Ting Leung, Huifang Liu, et al.
Autophagy|December 10, 2020
Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2<sup>R1441G</sup> miceHuifang Liu, Philip Wing-Lok Ho, Chi-Ting Leung, et al.
Brain and Behavior|January 10, 2023
In vivo overexpression of synaptogyrin-3 promotes striatal synaptic dopamine uptake in LRRK2<sup>R1441G</sup>  mutant mouse model of Parkinson's diseasePhilip Wing-Lok Ho, Lingfei Li, Hui-Fang Liu, et al.
Translational Neurodegeneration|February 1, 2022
LRRK2, GBA and their interaction in the regulation of autophagy: implications on therapeutics in Parkinson's diseaseShirley Yin-Yu Pang, Rachel Cheuk Nam Lo, Philip Wing-Lok Ho, et al.
NPJ Parkinson'S Disease|September 10, 2022
Long-term inhibition of mutant LRRK2 hyper-kinase activity reduced mouse brain α-synuclein oligomers without adverse effectsPhilip Wing-Lok Ho, Eunice Eun-Seo Chang, Chi-Ting Leung, et al.
Autophagy|February 26, 2021
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, et al.
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