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Chiara Brullo

Showing results (91-100 of 104) with videos related to

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Chemmedchem|February 26, 2013
A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitorsMattia Mori, Cristina Tintori, Robert Selwyne Arul Christopher, et al.
Journal of Medicinal Chemistry|March 30, 2011
Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization studyMarco Radi, Elena Dreassi, Chiara Brullo, et al.
Scientific Reports|April 13, 2017
Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's diseaseRoberta Ricciarelli, Chiara Brullo, Jos Prickaerts, et al.
Journal of Medicinal Chemistry|June 11, 2013
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutantMarco Radi, Cristina Tintori, Francesca Musumeci, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|January 17, 2025
Phosphodiesterase 4D inhibition improves the functional and molecular outcome in a mouse and human model of Charcot Marie Tooth disease 1 AMelissa Schepers, Tim Vangansewinkel, Karen Libberecht, et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|November 4, 2025
Prophylactic PDE4 and PDE4B inhibition reduce lesion size and neutrophil infiltration following ischemic stroke in male miceLaura Ponsaerts, Lotte Alders, Melissa Schepers, et al.
Journal of Medicinal Chemistry|March 3, 2006
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylationFabio Carraro, Antonella Naldini, Annalisa Pucci, et al.
Journal of Medicinal Chemistry|December 4, 2014
Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastomaCristina Tintori, Anna Lucia Fallacara, Marco Radi, et al.
Cellular and Molecular Life Sciences : CMLS|June 12, 2023
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathologyDean Paes, Melissa Schepers, Emily Willems, et al.
Journal of Medicinal Chemistry|October 13, 2007
Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in miceFabrizio Manetti, Annalisa Santucci, Giada A Locatelli, et al.
Pageof 11

Showing results (91-100 of 104) with videos related to

Sort By:
Pageof 11
Chemmedchem|February 26, 2013
A combination strategy to inhibit Pim-1: synergism between noncompetitive and ATP-competitive inhibitorsMattia Mori, Cristina Tintori, Robert Selwyne Arul Christopher, et al.
Journal of Medicinal Chemistry|March 30, 2011
Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization studyMarco Radi, Elena Dreassi, Chiara Brullo, et al.
Scientific Reports|April 13, 2017
Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's diseaseRoberta Ricciarelli, Chiara Brullo, Jos Prickaerts, et al.
Journal of Medicinal Chemistry|June 11, 2013
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutantMarco Radi, Cristina Tintori, Francesca Musumeci, et al.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|January 17, 2025
Phosphodiesterase 4D inhibition improves the functional and molecular outcome in a mouse and human model of Charcot Marie Tooth disease 1 AMelissa Schepers, Tim Vangansewinkel, Karen Libberecht, et al.
Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism|November 4, 2025
Prophylactic PDE4 and PDE4B inhibition reduce lesion size and neutrophil infiltration following ischemic stroke in male miceLaura Ponsaerts, Lotte Alders, Melissa Schepers, et al.
Journal of Medicinal Chemistry|March 3, 2006
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylationFabio Carraro, Antonella Naldini, Annalisa Pucci, et al.
Journal of Medicinal Chemistry|December 4, 2014
Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastomaCristina Tintori, Anna Lucia Fallacara, Marco Radi, et al.
Cellular and Molecular Life Sciences : CMLS|June 12, 2023
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathologyDean Paes, Melissa Schepers, Emily Willems, et al.
Journal of Medicinal Chemistry|October 13, 2007
Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in miceFabrizio Manetti, Annalisa Santucci, Giada A Locatelli, et al.
Pageof 11