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Current Opinion in Chemical Biology|August 17, 2019
Bifunctional chemical probes inducing protein-protein interactionsChiara Maniaci, Alessio Ciulli
Essays in Biochemistry|February 25, 2026
From molecular logic to therapeutic modulation: advances in Ub/UBL signallingBenjamin M Foster, Chiara Maniaci
Bioorganic & Medicinal Chemistry|March 4, 2019
Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACsMiriam Girardini, Chiara Maniaci, Scott J Hughes, et al.
ACS Chemical Biology|April 13, 2019
Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC DegraderHannah Tovell, Andrea Testa, Chiara Maniaci, et al.
Nucleic Acids Research|April 3, 2024
DEGRONOPEDIA: a web server for proteome-wide inspection of degronsNatalia A Szulc, Filip Stefaniak, Małgorzata Piechota, et al.
Nature Communications|October 12, 2017
Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradationChiara Maniaci, Scott J Hughes, Andrea Testa, et al.
ACS Medicinal Chemistry Letters|September 17, 2020
Understanding and Improving the Membrane Permeability of VH032-Based PROTACsVictoria G Klein, Chad E Townsend, Andrea Testa, et al.
Cell Chemical Biology|July 16, 2020
Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile SystemLuke M Simpson, Thomas J Macartney, Alice Nardin, et al.
Journal of Medicinal Chemistry|December 13, 2018
Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel-Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7Vittoria Zoppi, Scott J Hughes, Chiara Maniaci, et al.
Exploration of Targeted Anti-Tumor Therapy|September 1, 2022
The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like typeChiara Tarantelli, Eleonora Cannas, Hillarie Ekeh, et al.
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