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Journal of Clinical Pharmacology|July 26, 2023
Development and Verification of a Japanese Pediatric Physiologically Based Pharmacokinetic Model with Emphasis on Drugs Eliminated by Cytochrome P450 or Renal ExcretionTrevor N Johnson, Khaled Abduljalil, Xian Pan, et al.
Current Drug Metabolism|October 27, 2010
Methodologies for investigating drug metabolism at the early drug discovery stage: prediction of hepatic drug clearance and P450 contributionChie Emoto, Norie Murayama, Amin Rostami-Hodjegan, et al.
Drug Metabolism and Pharmacokinetics|December 25, 2004
In vitro inhibitory effect of 1-aminobenzotriazole on drug oxidations catalyzed by human cytochrome P450 enzymes: a comparison with SKF-525A and ketoconazoleChie Emoto, Shigeo Murase, Yasufusa Sawada, et al.
European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V|January 17, 2017
Arachidonic acid with taurine enhances pulmonary absorption of macromolecules without any serious histopathological damagesMasateru Miyake, Takanori Minami, Hiroyuki Yamazaki, et al.
European Journal of Medicinal Chemistry|April 5, 2016
Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure-activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivativesShigeo Hayashi, Katsuyo Ohashi, Sachiko Mihara, et al.
Drug Metabolism and Pharmacokinetics|December 20, 2013
Optimization of mycophenolic acid therapy using clinical pharmacometricsMin Dong, Tsuyoshi Fukuda, Alexander A Vinks
Current Drug Metabolism|September 12, 2012
Comparison of p450 enzymes between cynomolgus monkeys and humans: p450 identities, protein contents, kinetic parameters, and potential for inhibitory profilesChie Emoto, Noriaki Yoda, Yasuhiro Uno, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|October 11, 2016
Prediction of drug intestinal absorption in human using the Ussing chamber system: A comparison of intestinal tissues from animals and humansMasateru Miyake, Toshihisa Koga, Satoshi Kondo, et al.
Molecular and Cellular Neurosciences|January 12, 2011
Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephalyTsuyoshi Fukuda, Akinori Tokunaga, Reiko Sakamoto, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|February 14, 2012
Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymesNoriaki Yoda, Chie Emoto, Shoichi Date, et al.
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