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ACS Chemical Neuroscience|September 9, 2014
The potential of indole and a synthetic derivative for polyQ aggregation reduction by enhancement of the chaperone and autophagy systemsChih-Hsin Lin, Yih-Ru Wu, Pin-Jui Kung, et al.
International Journal of Molecular Sciences|October 16, 2024
Small Molecules Inducing Autophagic Degradation of Expanded Polyglutamine Protein through Interaction with Both Mutant ATXN3 and LC3Te-Hsien Lin, Wan-Ling Chen, Shao-Fan Hsu, et al.
Oxidative Medicine and Cellular Longevity|November 23, 2021
Novel Synthetic Coumarin-Chalcone Derivative (E)-3-(3-(4-(Dimethylamino)Phenyl)Acryloyl)-4-Hydroxy-2<i>H</i>-Chromen-2-One Activates CREB-Mediated Neuroprotection in A<i>β</i> and Tau Cell Models of Alzheimer's DiseaseYa-Jen Chiu, Te-Hsien Lin, Chiung-Mei Chen, et al.
Plos One|July 17, 2014
FBXO7 Y52C polymorphism as a potential protective factor in Parkinson's diseaseChiung-Mei Chen, I-Cheng Chen, Yi-Cheng Huang, et al.
Parkinsonism & Related Disorders|March 14, 2018
Genetic and functional characters of GRN p.T487I mutation in Taiwanese patients with atypical parkinsonian disordersKuo-Hsuan Chang, Guan-Chiun Lee, Chin-Chang Huang, et al.
Drug Design, Development and Therapy|March 26, 2016
The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer's diseaseKuo-Hsuan Chang, I-Cheng Chen, Hsuan-Yuan Lin, et al.
Cells|May 21, 2020
Lactulose and Melibiose Inhibit α-Synuclein Aggregation and Up-Regulate Autophagy to Reduce Neuronal VulnerabilityChiung Mei Chen, Chih-Hsin Lin, Yih-Ru Wu, et al.
European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|April 21, 2016
Identifying GSK-3β kinase inhibitors of Alzheimer's disease: Virtual screening, enzyme, and cell assaysChih-Hsin Lin, Yu-Shao Hsieh, Yih-Ru Wu, et al.
Neurotoxicology|June 25, 2018
The indole compound NC009-1 inhibits aggregation and promotes neurite outgrowth through enhancement of HSPB1 in SCA17 cells and ameliorates the behavioral deficits in SCA17 miceChiung-Mei Chen, Wan-Ling Chen, Chen-Ting Hung, et al.
Aging|February 15, 2019
Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse modelsChiung-Mei Chen, Wan-Ling Chen, Chen-Ting Hung, et al.
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