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Journal of Natural Products|September 28, 2002
Dammarane-type Saponins from Panax japonicus and their neurite outgrowth activity in SK-N-SH cellsKun Zou, Shu Zhu, Meselhy R Meselhy, et al.Organic Letters|August 6, 2009
Synthesis of sominone and its derivatives based on an RCM strategy: discovery of a novel anti-Alzheimer's disease medicine candidate "denosomin"Yuji Matsuya, Yu-ichiro Yamakawa, Chihiro Tohda, et al.Frontiers in Pharmacology|May 31, 2021
A Novel Heptapeptide, GPPGPAG Transfers to the Brain, and Ameliorates Memory Dysfunction and Dendritic Atrophy in Alzheimer's Disease Model MiceChihiro Tohda, Chisato Kogure, Kaori Nomoto, et al.Nutrients|January 26, 2020
Combined Treatment with Two Water Extracts of Eleutherococcus senticosus Leaf and Rhizome of Drynaria fortunei Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind Study in Healthy AdultsChihiro Tohda, Mie Matsui, Yuna Inada, et al.Journal of Natural Products|July 12, 2016
Effects of Oleanane-Type Triterpene Saponins from the Leaves of Eleutherococcus senticosus in an Axonal Outgrowth AssayYue-Wei Ge, Chihiro Tohda, Shu Zhu, et al.Bioorganic & Medicinal Chemistry Letters|December 7, 2011
Synthesis of dihydrofuran-fused perhydrophenanthrenes having a phenolic hydroxyl group as a novel anti-Alzheimer's disease agentKenji Sugimoto, Kosuke Tamura, Naoki Ohta, et al.Organic Letters|November 21, 2015
Synthesis of Denosomin-Vitamin D3 Hybrids and Evaluation of Their Anti-Alzheimer's Disease ActivitiesKenji Sugimoto, Hisanari Yajima, Yusuke Hayashi, et al.Molecular Pharmacology|March 3, 2023
Alkannin Attenuates Amyloid β Aggregation and Alzheimer's Disease PathologyToru Hosoi, Kyosuke Yazawa, Michihiro Imada, et al.British Journal of Pharmacology|September 18, 2012
A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte-secreted vimentinKiyoshi Teshigawara, Tomoharu Kuboyama, Michiko Shigyo, et al.Nutrients|May 25, 2019
Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the BrainYui Yamauchi, Yue-Wei Ge, Kayo Yoshimatsu, et al.Pageof 10