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Cell Metabolism|September 19, 2017
A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural ProductMaria V Liberti, Ziwei Dai, Suzanne E Wardell, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|October 10, 2022
Clinical Efficacy and Whole-Exome Sequencing of Liquid Biopsies in a Phase IB/II Study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor-Positive Breast CancerJunko Tsuji, Tianyu Li, Albert Grinshpun, et al.
Chemistry & Biology|April 25, 2009
Differential presentation of protein interaction surfaces on the androgen receptor defines the pharmacological actions of bound ligandsJohn David Norris, James David Joseph, Andrea Barreto Sherk, et al.
Journal of Medicinal Chemistry|March 16, 2017
Discovery of an Acrylic Acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERα+ Breast CancerHeather E Burks, Tinya Abrams, Christina A Kirby, et al.
The Journal of Clinical Investigation|May 3, 2017
Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancerJohn D Norris, Stephanie J Ellison, Jennifer G Baker, et al.
Journal of Medicinal Chemistry|November 27, 2023
Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2)Young Chen, Brandon Whitefield, Erin Nevius, et al.
Nature Communications|July 25, 2023
Macrophage-to-endothelial cell crosstalk by the cholesterol metabolite 27HC promotes atherosclerosis in male miceLiming Yu, Lin Xu, Haiyan Chu, et al.
Molecular Metabolism|July 20, 2024
Esrra regulates Rplp1-mediated translation of lysosome proteins suppressed in metabolic dysfunction-associated steatohepatitis and reversed by alternate day fastingMadhulika Tripathi, Karine Gauthier, Reddemma Sandireddy, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 18, 2026
Regulation of the immune CD155-CD226-TIGIT axis by cyclin D-CDK4/6Anne Fassl, Miriam Palacios Espinoza, Deborah Butter, et al.
Science Translational Medicine|December 16, 2016
PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translationGray R Anderson, Suzanne E Wardell, Merve Cakir, et al.
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