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Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 9, 2014
Validation of uPA/SCID mouse with humanized liver as a human liver model: protein quantification of transporters, cytochromes P450, and UDP-glucuronosyltransferases by LC-MS/MSSumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, et al.
Clinical and Translational Science|June 3, 2021
Prediction of human pharmacokinetics for low-clearance compounds using pharmacokinetic data from chimeric mice with humanized liversKosuke Yoshida, Yuki Doi, Norihiko Iwazaki, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 1, 2012
Predictability of metabolism of ibuprofen and naproxen using chimeric mice with human hepatocytesSeigo Sanoh, Aya Horiguchi, Kazumi Sugihara, et al.
The American Journal of Pathology|March 21, 2015
Novel robust in vitro hepatitis B virus infection model using fresh human hepatocytes isolated from humanized miceYuji Ishida, Chihiro Yamasaki, Ami Yanagi, et al.
Journal of Virology|April 29, 2021
Understanding Hepatitis B Virus Dynamics and the Antiviral Effect of Interferon Alpha Treatment in Humanized Chimeric MiceVladimir Reinharz, Yuji Ishida, Masataka Tsuge, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 17, 2015
Development of Murine Cyp3a Knockout Chimeric Mice with Humanized LiverKota Kato, Masato Ohbuchi, Satoko Hamamura, et al.
Plos Pathogens|January 9, 2025
Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx geneMin Zhang, Karim Mouzannar, Zhensheng Zhang, et al.
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