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Neuropharmacology|September 5, 2017
Methoxetamine produces rapid and sustained antidepressant effects probably via glutamatergic and serotonergic mechanismsChrislean Jun Botanas, June Bryan de la Peña, Raly James Custodio, et al.
Behavioural Brain Research|July 13, 2016
A tryptic hydrolysate from bovine milk αs1-casein enhances pentobarbital-induced sleep in mice via the GABAA receptorIrene Joy I Dela Peña, Hee Jin Kim, June Bryan de la Peña, et al.
Neuroscience|August 24, 2018
Overexpression of the Thyroid Hormone-Responsive (THRSP) Gene in the Striatum Leads to the Development of Inattentive-like Phenotype in MiceRaly James Perez Custodio, Chrislean Jun Botanas, June Bryan de la Peña, et al.
Psychopharmacology|December 13, 2019
4-MeO-PCP and 3-MeO-PCMo, new dissociative drugs, produce rewarding and reinforcing effects through activation of mesolimbic dopamine pathway and alteration of accumbal CREB, deltaFosB, and BDNF levelsArvie Abiero, Chrislean Jun Botanas, Raly James Custodio, et al.
Addiction Biology|November 22, 2019
25B-NBOMe, a novel N-2-methoxybenzyl-phenethylamine (NBOMe) derivative, may induce rewarding and reinforcing effects via a dopaminergic mechanism: Evidence of abuse potentialRaly James Perez Custodio, Leandro Val Sayson, Chrislean Jun Botanas, et al.
Psychopharmacology|March 21, 2019
The novel methoxetamine analogs N-ethylnorketamine hydrochloride (NENK), 2-MeO-N-ethylketamine hydrochloride (2-MeO-NEK), and 4-MeO-N-ethylketamine hydrochloride (4-MeO-NEK) elicit rapid antidepressant effects via activation of AMPA and 5-HT<sub>2</sub> receptorsLeandro Val Sayson, Chrislean Jun Botanas, Raly James Perez Custodio, et al.
Biomolecules & Therapeutics|February 8, 2017
The Abuse Potential of α-Piperidinopropiophenone (PIPP) and α-Piperidinopentiothiophenone (PIVT), Two New Synthetic Cathinones with Piperidine Ring SubstituentChrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, et al.
Pharmacology, Biochemistry, and Behavior|January 9, 2017
The abuse potential of two novel synthetic cathinones with modification on the alpha-carbon position, 2-cyclohexyl-2-(methylamino)-1-phenylethanone (MACHP) and 2-(methylamino)-1-phenyloctan-1-one (MAOP), and their effects on dopaminergic activityChrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, et al.
Behavioural Brain Research|October 15, 2016
A novel synthetic cathinone, 2-(methylamino)-1-(naphthalen-2-yl) propan-1-one (BMAPN), produced rewarding effects and altered striatal dopamine-related gene expression in miceChrislean Jun Botanas, Seong Shoon Yoon, June Bryan de la Peña, et al.
Neuropharmacology|May 23, 2021
R (-)-methoxetamine exerts rapid and sustained antidepressant effects and fewer behavioral side effects relative to S (+)-methoxetamineChrislean Jun Botanas, Raly James Perez Custodio, Hee Jin Kim, et al.
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