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Journal of Alzheimer'S Disease : JAD
|
August 4, 2011
A nuclear function for the presenilin 1 neuronal partner NPRAP/δ-catenin
Carolina Koutras, Christian B Lessard, Georges Lévesque
Cellular Signalling
|
December 17, 2004
The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells
Christian B Lessard, Marc P Lussier, Sylvie Cayouette, et al.
Plos One
|
December 19, 2015
γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP)
Christian B Lessard, Barbara A Cottrell, Hiroko Maruyama, et al.
The Journal of Biological Chemistry
|
June 7, 2019
Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells
Christian B Lessard, Edgardo Rodriguez, Thomas B Ladd, et al.
Alzheimer'S Research & Therapy
|
May 21, 2020
γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not
Christian B Lessard, Edgardo Rodriguez, Thomas B Ladd, et al.
The Journal of Biological Chemistry
|
August 27, 2011
Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein
Sarah A Sagi, Christian B Lessard, Kellen D Winden, et al.
EMBO Molecular Medicine
|
May 26, 2017
γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct
Yong Ran, Fokhrul Hossain, Antonio Pannuti, et al.
Alzheimer'S Research & Therapy
|
February 4, 2019
Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph
Lorenza Magno, Christian B Lessard, Marta Martins, et al.
EMBO Molecular Medicine
|
October 21, 2018
High-affinity interactions and signal transduction between Aβ oligomers and TREM2
Christian B Lessard, Samuel L Malnik, Yingyue Zhou, et al.
Acta Neuropathologica
|
January 26, 2021
Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions
Cara L Croft, Marshall S Goodwin, Daniel H Ryu, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 13) with videos related to
Sort By:
Page
of 2
Journal of Alzheimer'S Disease : JAD
|
August 4, 2011
A nuclear function for the presenilin 1 neuronal partner NPRAP/δ-catenin
Carolina Koutras, Christian B Lessard, Georges Lévesque
Cellular Signalling
|
December 17, 2004
The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells
Christian B Lessard, Marc P Lussier, Sylvie Cayouette, et al.
Plos One
|
December 19, 2015
γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP)
Christian B Lessard, Barbara A Cottrell, Hiroko Maruyama, et al.
The Journal of Biological Chemistry
|
June 7, 2019
Individual and combined presenilin 1 and 2 knockouts reveal that both have highly overlapping functions in HEK293T cells
Christian B Lessard, Edgardo Rodriguez, Thomas B Ladd, et al.
Alzheimer'S Research & Therapy
|
May 21, 2020
γ-Secretase modulators exhibit selectivity for modulation of APP cleavage but inverse γ-secretase modulators do not
Christian B Lessard, Edgardo Rodriguez, Thomas B Ladd, et al.
The Journal of Biological Chemistry
|
August 27, 2011
Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein
Sarah A Sagi, Christian B Lessard, Kellen D Winden, et al.
EMBO Molecular Medicine
|
May 26, 2017
γ-Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct
Yong Ran, Fokhrul Hossain, Antonio Pannuti, et al.
Alzheimer'S Research & Therapy
|
February 4, 2019
Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph
Lorenza Magno, Christian B Lessard, Marta Martins, et al.
EMBO Molecular Medicine
|
October 21, 2018
High-affinity interactions and signal transduction between Aβ oligomers and TREM2
Christian B Lessard, Samuel L Malnik, Yingyue Zhou, et al.
Acta Neuropathologica
|
January 26, 2021
Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions
Cara L Croft, Marshall S Goodwin, Daniel H Ryu, et al.
Page
of 2