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Nature Communications|March 27, 2026
Smad7-based biologic targeting epidermis and stroma promotes healing of diabetic wounds in mice and pigsYao Ke, Ben-Zheng Li, Fulun Li, et al.
Plos One|August 10, 2011
Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivoChristian D Young, Andrew S Lewis, Michael C Rudolph, et al.
International Journal of Radiation Oncology, Biology, Physics|June 18, 2025
Identifying Pathogenic Contributors of Radiodermatitis Ameliorated by Smad7-Based Targeting in Canine and Mouse ModelsYao Ke, Mary-Keara Boss, Braden Burdekin, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 7, 2018
Smad7 Promotes Healing of Radiotherapy-Induced Oral Mucositis without Compromising Oral Cancer Therapy in a Xenograft Mouse ModelJingjing Luo, Li Bian, Melanie A Blevins, et al.
Cancer Letters|May 30, 2026
Ectopic integrin β1 overproduction by squamous carcinoma cells contributes to immune evasion-associated metastasisJohn D Aleman, Christian D Young, Yao Ke, et al.
The Journal of Pathology|August 14, 2025
Activation of PI3K and deletion of p53 in keratin 15-expressing mouse mammary cells induces tumor heterogeneity and plasticity modeling metaplastic breast cancerKhoa A Nguyen, Lauren E McLemore, Yao Ke, et al.
Cancer Letters|November 23, 2024
MHC class I upregulation contributes to the therapeutic response to radiotherapy in combination with anti-PD-L1/anti-TGF-β in squamous cell carcinomas with enhanced CD8 T cell memory-driven responseHanne T Lind, Spencer C Hall, Alexander A Strait, et al.
International Journal of Molecular Sciences|September 12, 2020
Deletion of p53 and Hyper-Activation of PIK3CA in Keratin-15+ Stem Cells Lead to the Development of Spontaneous Squamous Cell CarcinomaSamantha M Y Chen, Bian Li, Andrew G Nicklawsky, et al.
Cancer Research|May 2, 2013
Conditional loss of ErbB3 delays mammary gland hyperplasia induced by mutant PIK3CA without affecting mammary tumor latency, gene expression, or signalingChristian D Young, Adam D Pfefferle, Philip Owens, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 14, 2013
Mutant PIK3CA accelerates HER2-driven transgenic mammary tumors and induces resistance to combinations of anti-HER2 therapiesAriella B Hanker, Adam D Pfefferle, Justin M Balko, et al.
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